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    $98.00 $75.00
    1. Essential Cell Biology, Second
    $130.00 $88.95
    2. Genes VIII
    $135.95 $45.00
    3. Introduction to Microbiology :
    $119.95
    4. A-Z of Quantitative PCR (IUL Biotechnology,
    $19.79 $9.45 list($29.99)
    5. Bioinformatics for Dummies
    $134.00 $55.00
    6. Introduction to Biomedical Equipment
    $150.00 $123.52
    7. Biological Performance of Materials:
    $16.32 $12.32 list($24.00)
    8. Rebuilt : How Becoming Part Computer
    $120.00 $109.85
    9. Design and Development of Medical
    $213.00 $161.25
    10. Biochemistry & Molecular Biology
    $213.00 $161.25
    11. Biochemistry & Molecular Biology
    $114.95 $49.99
    12. Medical Instrumentation : Application
    $76.25 $65.39
    13. Field Methods in Archaeology
    $55.00 $38.69
    14. Mechanics of the Cell
    $55.96 list($69.95)
    15. Monte Carlo Methods in Financial
    $160.66 $85.00 list($175.00)
    16. Biocatalysis
    $97.81 $59.50
    17. Basic Biomechanics with Dynamic
    $16.47 $15.65 list($24.95)
    18. More Than Human : Embracing the
    $34.65 $32.01 list($45.00)
    19. Biological Sequence Analysis :
    $12.24 list($18.00)
    20. Biodiesel: Growing A New Energy

    1. Essential Cell Biology, Second Edition
    by Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Dennis Bray, Karen Hopkin, Keith Roberts, Peter Walter
    list price: $98.00
    our price: $98.00
    (price subject to change: see help)
    Asin: 081533480X
    Catlog: Book (2003-10-01)
    Publisher: Garland Science/Taylor & Francis Group
    Sales Rank: 40100
    Average Customer Review: 4.64 out of 5 stars
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    Book Description

    Essential Cell Biology, Second Edition contains basic, core knowledge about how cells work. It has a proven track record in providing students with a conceptual and accessible grounding in cell biology. The text and figures have been prepared to be easy-to-follow, accurate, clear and engaging for the introductory student. Each section follows logically from the previous one, telling a story, rather than being a collection of facts. Questions integrated throughout each chapter encourage the reader to pause, think about what they have read, and attempt to apply the new knowledge in ways that test their understanding. Based on user feedback, the Second Edition now offers increased coverage of genetics and more experimental background. It is completely up-to-date. ... Read more

    Reviews (14)

    5-0 out of 5 stars A MUST HAVE FOR ANY EDUCATED PERSON
    A gem of a book. It puts at the hands of lay people the wonders of molecular biology. The best way of spending $65 I can think of.

    The text is a most refined product distilled by an all-star team of leading scientists. Oriented towards the lay person or the would be specialist, it is simple, unpretentious, sometimes even funny, but always powerfully explanatory. The diagrams are exceptionally clear (a must for explaining such complex subjects) and the photographs are astounding. Love for their subject and passion for teaching are present all along. And mysticism is always around the corner...

    If you have ever wondered things like "What are exactly chromosomes?", "How do exactly enzymes work in the cell?", or "How the hell does all this machinery work at a purely chemical level ?" and you are not quite satisfied with popular science books, this one is for you. It will answer these questions and much, much more.

    An enjoyable, deeply satisfying tour the force through the molecular level of all living organisms.

    Don't miss it!

    5-0 out of 5 stars A lively and clear introduction to cell biology
    I read this book during the summer prior to me senior year in high school, and literally could not put it down. I read the whole work cover-to-cover in a week.

    Going in, my background in biology was an introductory cell biology course and my background in chemistry was an introductory chemistry class. That I had little formal training in the sciences was irrelevant when reading this; it explains all the concepts so clearly that I think even a person with no background in science at all could understand it. The diagrams and photos are well-done and highly pertinent.

    This is not to say that this book is only for non-scientists. Indeed, I even used knowledge gleaned from this fantastic book to teach my teachers a thing or two. Perhaps the section on muscle contraction is the best written of all - no other book I have ever seen comes close to this in clarity, and this section was one that I recommended to my Anatomy and Physiology teacher for clarification about a few concepts.

    I am soon to be a sophomore in college, and this book continues to inspire me on my path to be a professor (I study chemistry with an emphasis on chemical biology). This book was invaluable even in a rigorous microbiology course, not to mention other introductory courses.

    In summary, I rarely leave home for extended periods without this text (literally). If there is ONE BOOK that you should buy for studying cellular and molecular biology, let it be this one (or, if you are so inclined, its larger brother, Molecular Biology of the Cell).

    5-0 out of 5 stars A great help for a 1st year Med Student
    "Essential Cell Biology" by Bruce Alberts literally saved my 1st semester. The course went hard and the lectures were long and boring. And then - I opened the Essential, started reading, and suddenly things got clear for me. I got an A on the test, and now I know my Cell Biology well - all thanks to this book. Strongly recommended!!!

    5-0 out of 5 stars A textbook that inspires you to think
    This book contains essential stuff enough for medical students, although not enough for biochemistry or biology students. But this book is still useful because whenever you read the book, you will be inspired to that particular field. It is written not as tedious and complex as those "big" textbooks. Easy to read. Interesting. I highly recommend this textbook.

    But if you are looking for every detail in molecular biology, this book is not satisfactory.

    3-0 out of 5 stars A fairly useful introduction to cell biology
    This is a beautifully presented book. My students like it enormously, because of the conversational style, the illustrations, and the overall readibility -and this is perhaps the highest aim a textbook can aspire to achieve.

    However, I find that the authors have gone too far in their attempt to abridge and simplify their previous opus -Molecular Biology of the Cell (MBOC): some topics are insufficiently or superficially discussed. Also, the style is slightly verbose at times. Finally, I think that the book could benefit from some reorganization.

    The following examples illustrate my point.

    *Osmosis is given a very brief mention.(p 382).
    *The repulsion for anything mathematic continues the tradition started by MBOC. The Nernst equation, is given just a little box in page 393. The Donnan effect doesn't even have a walk-on part.
    *The discussion of action potential contains the usual story of the voltage gated K+ channels, when these channels are not found in myelinated mammalian neurons.
    *Myelin itself is not even mentioned.
    *The discussion on G protein-linked receptors -a key topic- is very superficial.
    *Membrane potential is introduced in a rather convoluted fashion. Furthermore, the concept is used several times before it is finally explained.
    *Certain sections may leave the reader confused. For example p53 is described as a gene regulatory protein which arrests the cycle when DNA damage occurs (p 580). But when tumor suppressor genes are discussed, only retinoblastoma is given as an example, which would tend to convey the mistaken idea that p53 is not a tumor suppressor gene. ... Read more


    2. Genes VIII
    by Benjamin Lewin
    list price: $130.00
    our price: $130.00
    (price subject to change: see help)
    Asin: 0131439812
    Catlog: Book (2003-12-15)
    Publisher: Prentice Hall
    Sales Rank: 49066
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    Book Description

    The unique feature of this book's first edition was the presentation of a unified approach to the molecular biology of prokaryotes and eukaryotes. The success of this approach, and its continuation, is the result of a long string of discoveries showing similarities in solutions to biological problems that often extend across many or even all species.A six-part organization covers genes, proteins, gene expression, DNA, the nucleus, and cells.For individuals in the science community interested in genetics. ... Read more


    3. Introduction to Microbiology : A Case-History Study Approach (with CD-ROM and InfoTrac)
    by John L. Ingraham, Catherine A. Ingraham
    list price: $135.95
    our price: $135.95
    (price subject to change: see help)
    Asin: 0534394655
    Catlog: Book (2003-04-14)
    Publisher: Brooks Cole
    Sales Rank: 167804
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    Book Description

    Would you like to bring guest lectures like researchers, physicians, or fellow instructors into you microbiology course? With this third edition of INTRODUCTION TO MICROBIOLOGY you get the perspective of all of those three professionals. John Ingraham, a professor of microbiology at University of California at Davis, and Catherine Ingraham, his daughter and a practicing physician, utilize their experience within a case history approach complemented by a great technology package. Each chapter in INTRODUCTION TO MICROBIOLOGY now consistently begins with a case history, which John Ingraham has found very motivatonal to students who are new to the study ofbasic science. Because Catherine Ingraham studied to become a physician by interviewing patients, determining causes and implementing solutions, she knows mastry comes from high interest human stories rather than clinical presentations. Many of the case histories found in this book are taken from Catherine's experience as a physician. This combination of experiences and talent brings a case-based quality to every lecture and homework session.This unique author team also provides up-to-the-minute currency. Coverage of new microbial "events" such as biological warfare, studied by John and its effects prepared for in Catherine's office, keeps students interested. The authors also highlight reemerging diseases, such as tuberculoses and smallpox.As with previous editions, this book takes a "body systems" organization. Students are exposed to the unknown, the world of the microbes, through the known, and the different parts of their own bodies. And, because art is so important, there is again a multimedia manager with this title, but with more exciting capabilities than ever before. Instructors receive powerful PowerPoint slides for all the illustrations, tables and figures from the text, plus several animations are at your fingertips. ... Read more


    4. A-Z of Quantitative PCR (IUL Biotechnology, No. 5)
    list price: $119.95
    our price: $119.95
    (price subject to change: see help)
    Asin: 0963681788
    Catlog: Book (2004-07)
    Publisher: International University Line
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    Book Description

    This book is a comprehensive manual to allow both the novice researcher and the expert to set up and carry out quantitative PCR assays from scratch. However, this book also sets out to explain as many features of qPCR as possible, provide alternative viewpoints, methods, and aims to simulate the researchers into generating, interpreting, and publishing data that are reproducible, reliable, and biologically meaningful ... Read more


    5. Bioinformatics for Dummies
    by Jean-MichelClaverie, CedricNotredame, Jean-Michel Claverie, Cedric Notredame
    list price: $29.99
    our price: $19.79
    (price subject to change: see help)
    Asin: 0764516965
    Catlog: Book (2003-01-15)
    Publisher: For Dummies
    Sales Rank: 11685
    Average Customer Review: 5 out of 5 stars
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    Book Description

    Bioinformatics – the process of searching biological databases, comparing sequences, examining protein structures, and researching biological questions with a computer – is one of the marvels of modern technology that can save you months of lab work. And the most amazing part is that, if you know how, you can use highly sophisticated programs over the Internet without paying a dime and sometimes, without installing anything new on your own computer. All you need to know is how to use these technological miracles.

    That's where Bioinformatics For Dummies comes in. If you want to know what bioinformatics is all about and how to use it without wading through pages of computer gibberish or taking a course full of theory, this book has the answers in plain English. You'll find out how to

    • Use Internet resources
    • Understand bioinformatics jargon
    • Research biological databases
    • Locate the sequences you need
    • Perform specific tasks, step by step

    Written by two experts who helped develop the science, Bioinformatics For Dummies is all about getting things done. If you're just getting your feet wet, start at the beginning with a quick review of those necessary parts of microbiology and an overview of the tools available. If you already know what you want to do, you can go directly to a chapter that shows you how. Get the lowdown on

    • Researching and analyzing DNA and protein sequences
    • Gathering information from all published sources
    • Searching databases for similar sequences and acquiring information about gene functions through sequence comparisons
    • Producing and editing multiple sequence comparisons for presentation
    • Predicting protein structures and RNA structures
    • Doing phylogenetic analysis

    With an Internet connection and Bioinformatics For Dummies, you'll discover how to peruse databases that contain virtually everything known about human biology. It's like having access to the world's largest lab, right from your desk. This book is your lab assistant – one that never takes a day off, never argues when you ask it for help, and won't demand a benefits package. ... Read more

    Reviews (6)

    5-0 out of 5 stars Bioinformatics for Dummies by J.M. Claverie & C. Notredame
    "Bioinformatics for Dummies" is an excellent resource. It is clear, easy to read, well organized and illustrated. I was particularly pleased by the colloquial tone of the writing: in addition to being informative, it was fun to read!

    As a scientist who spends at least half of my time BLASTing, I also read it for accuracy and found it to almost error-free (any errors were in the figures). Additionally, most of the web pages were up-to-date, although as time passes the links will decay and web pages will change their look. In addition, the book contained enough in-depth content to teach me several new tricks of the trade.

    Further, I believe the book had sufficient background material to educate the novice. To test this, I gave the manual to a material science chemist and he was able to understand the material, at least until he decided it was more than he wanted to know and quit reading.

    This is a useful text for those who want to know more than an operational definition of bioinformatics and a must for the library of all bioinformatics users.

    5-0 out of 5 stars Walking amongst Dummys
    I'm glad I bought this book and I will continue to refer to it. The remit of the Dummies series is to provide a guide to its subject matter without any great fuss. The text focuses on practical techniques without unnecessary diversion into the detail of molecular biology or computer science. In this respect it would have been a difficult book to author, readers having come from one discipline or the other. I agree with previous reviewers that this is well worth reading before doing a bioinformatics course or degree. Bioinformatics is a new field, and this book has delivered a useful introduction to it without recourse to expensive textbooks full of unreadable filler.

    5-0 out of 5 stars A great resource for teachers too!
    I have used databases before (mostly NCBI, TIGR and SWISS PROT) and yet, this book (presumably for dummies) has shown me so much more(which say a lot about me)! It is accurate and gives good step by step guide to how to perform many tasks - from how to find a gene to using the analysis tools and to exploring some of the newer features of these databases - and the areas like you have never looked into before.
    It is a well-researched book and the authors are clearly knowledgeable in this area.

    Even though I have been for a 4-day bioinformatics course (6 months ago), which I thought was pretty good, this book still had so much to offer. Using this book, I was easily able to substitute the proteins of my interest into their examples and generated meaningful hits.

    The book also covers deeper and more advanced features of BLAST, discusses sequence alignments using several types of algorithm and even has a section on 3D structures. Towards the end of book - it features a section on working with mRNA and building phylogenetics trees - which again are excellent resources for teachers involved in teaching beginners molecular biology.

    I am a teacher teaching at a Pre-unversity level. The way the book is structured also lends its material to be modified into lesson materials for training students.

    It is really a great book! Worth every dollar I spent on it!

    5-0 out of 5 stars Get this book first, before enrolling in an expensive course
    This book will get you up and running on Bioinformatics in no time. I wish I got this book before I enrolled in a $$$$$ Bioinformatics course. I got more knowledge and information from this book $$$$$ than the course! And I am just in chapter 5 of the book and I'm more than half way through that $$$$$ course.

    5-0 out of 5 stars Great book-- Technical without the Computer-ese
    I got this book a week ago because one of my profs offered to buy it for a volunteer who was willing to check it out and then make a recommendation on it to the rest of the class. I'm glad I volunteered, and I'm encouraging my classmates to get their hands on a copy. This book wasn't boring. It was completely hands on, and it addressed the topic from the perspective of a biologist, not a technophile-- which was exactly what I needed. It helped me reconcile my love for pure science with my increasing anxiety about needing to be so darn computer proficient to have any kind of job I can apply my degree to these days. I'm glad I got a hold of it early in the semester. I think it's going to really impact my grade in the class-- Oh, and my understanding of bioinformatics! ... Read more


    6. Introduction to Biomedical Equipment Technology (4th Edition)
    by Joseph J. Carr, John M. Brown
    list price: $134.00
    our price: $134.00
    (price subject to change: see help)
    Asin: 0130104922
    Catlog: Book (2000-05-30)
    Publisher: Prentice Hall
    Sales Rank: 181236
    Average Customer Review: 4 out of 5 stars
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    Reviews (1)

    4-0 out of 5 stars Excellent book - But it could use a "cosmetic" update
    Good subject coverage, knowledgeable author, and plenty of uncluttered figures makes this book very worthwhile. The only thing missing from this excellent book is an update. Although this is the third edition (1998), almost all of the equipment photographs are from the early-to-mid 1970's. An extensive and broad Suggested Reading section follows most chapters but again far far too many references are to early 1970's books and manuals. An update could earn this book a 5+ rating. ... Read more


    7. Biological Performance of Materials: Fundamentals of Biocompatibility
    by Jonathan Black
    list price: $150.00
    our price: $150.00
    (price subject to change: see help)
    Asin: 0824771060
    Catlog: Book (1999-07-15)
    Publisher: Marcel Dekker
    Sales Rank: 852573
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    8. Rebuilt : How Becoming Part Computer Made Me More Human
    by Michael Chorost
    list price: $24.00
    our price: $16.32
    (price subject to change: see help)
    Asin: 0618378294
    Catlog: Book (2005-06-02)
    Publisher: Houghton Mifflin
    Sales Rank: 52378
    Average Customer Review: 4.5 out of 5 stars
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    Book Description

    Michael Chorost became a cyborg on October 1, 2001, the day his new ear was booted up. Born hard of hearing in 1964, he went completely deaf in his thirties. Rather than live in silence, he chose to have a computer surgically embedded in his skull to artificially restore his hearing.

    This is the story of Chorost's journey -- from deafness to hearing, from human to cyborg -- and how it transformed him. The melding of silicon and flesh has long been the stuff of science fiction. But as Chorost reveals in this witty, poignant, and illuminating memoir, fantasy is now giving way to reality.

    Chorost found his new body mystifyingly mechanical: kitchen magnets stuck to his head, and he could plug himself directly into a CD player. His hearing was routinely upgraded with new software. All this forced him to confront complex questions about humans in the machine age: When the senses become programmable, can we trust what they tell us about the world? Will cochlear implants destroy the signing deaf community? And above all, are cyborgs still human?

    A brilliant dispatch from the technological frontier, Rebuilt is also an ode to sound. Whether Chorost is adjusting his software in a desperate attempt to make the world sound "right" again, exploring the neurobiology of the ear, or reflecting on the simple pleasure of his mother's voice, he invites us to think about what we hear -- and how we experience the world -- in an altogether new way.

    Brimming with insight and written with dry, self-deprecating humor, this quirky coming-of-age story unveils, in a way no other book has, the magnificent possibilities of a new technological era.
    ... Read more

    Reviews (3)

    5-0 out of 5 stars what it means to be human
    I got home at 7:30pm frantic because my flight to Singapore was to
    depart at 6am, and found my preordered copy of "Rebuilt" from Amazon
    on the stoop.I hadn't packed and still had tons of email to go, on
    top of a couple of administrative emergencies.I was hoping to get
    to bed by 10pm.But instead, I stayed up until 1:30am reading
    Rebuilt, left in the morning with god-knows-what-all in my luggage,
    and finished it on the plane having not slept in transit at all.
    This book is seriously good.It's the first book that's ever made
    anything related to postmodern literary theory interesting to me.I
    laughed out loud at least a half dozen times.

    Yes, the book is by someone who's literally experienced one of the
    first mindmelds with a computer. Yes, the book has to do with
    deafness. Yes, the book looks at literature, and philosophy. But it's
    really one man's story and something that touches every one of us,
    which is what it means to be human--alone, together, and with
    our technologies. What a masterpiece.

    4-0 out of 5 stars An Amazingly Personal Look At Health and Technology
    I was skeptical at first when I was given this book but once I started the book I was amazed. I went in thinking what's the big deal about getting a cochlear implant and left trying to figure out "what is reality". Chorost does a great job infusing the book with his wit. He does seem to be uniquely qualified to write about this topic (with his background in technology). The book shines when he writes about his personal experiences. Two Thumbs Up.

    5-0 out of 5 stars Everybody should read this book
    This book isn't perfect.If I was Chorost's editor, I'd have told him to cut a few things & beef up other parts (and particularly told him "Less about the girls, more about the code"!Chorost seems to have underrated the interesting-ness of his insights as a guy who knows about software and overrated the interest of online dating; cf. "Genes, Girls and Gamow," a similar exercise...).But that said, this is one of the most striking and memorable books I've read for ages.Chorost is the perfect person to write this book, and his insights into the wonders & difficulties of the cochlear implant should be required reading for EVERYBODY who has an interest in biotechnology, language, education, neurology, etc.A real must-read. ... Read more


    9. Design and Development of Medical Electronic Instrumentation: A Practical Perspective of the Design, Construction, and Test of Medical Devices
    by DavidPrutchi, MichaelNorris
    list price: $120.00
    our price: $120.00
    (price subject to change: see help)
    Asin: 0471676233
    Catlog: Book (2004-11-05)
    Publisher: Wiley-Interscience
    Sales Rank: 237412
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    Book Description

    Design and Development of Medical Electronic Instrumentation fills a gap in the existing medical electronic devices literature by providing background and examples of how medical instrumentation is actually designed and tested. The book includes practical examples and projects, including working schematics, ranging in difficulty from simple biopotential amplifiers to computer-controlled defibrillators. Covering every stage of the development process, the book provides complete coverage of the practical aspects of amplifying, processing, simulating and evoking biopotentials. In addition, two chapters address the issue of safety in the development of electronic medical devices, and providing valuable insider advice. ... Read more


    10. Biochemistry & Molecular Biology of Plants
    list price: $213.00
    our price: $213.00
    (price subject to change: see help)
    Asin: 0943088372
    Catlog: Book (2002-05-10)
    Publisher: John Wiley & Sons
    Sales Rank: 550219
    Average Customer Review: 4.33 out of 5 stars
    US | Canada | United Kingdom | Germany | France | Japan

    Book Description

    Biochemistry Molecular Biology of Plants is a major contribution to the plant sciences literature, superbly edited by three distinguished scientists, Bob B. Buchanan, Wilhelm Gruissem, and Russell L. Jones, with contributions from more than 50 world-renowned scientists. With over 1,400 pages, 1,100 full-colour original drawings and 500 photographs this work qualifies, in the words of the Science reviewer, as:

    "an essential reference for practicing plant biologists and for the increasing number of scientists from other disciplines who are entering the field of plant biology. To exploit fully the wealth of new information provided by the genome projects and to integrate the metabolic, regulatory, and signal transduction pathways of complex organisms, biologists will require a solid command of biochemistry and physiology. For this reason, the publication of Biochemistry Molecular Biology of Plants could not have come at a more opportune and auspicious time."

    This book is meticulously organised and richly illustrated, useful both for teaching and for reference. The multi-authored work provides a contemporary view of its subject, including molecular biology, cell biology, and plant physiology, integrated around the themes of:

    • compartmentation
    • cell reproduction
    • energetics
    • metabolism
    • development
    Read the words of the reviewer in CELL:

    "The great strength of this book is that it has integrated its three major components (molecular biology, cell biology, and plant biochemistry) in each of the 24 chapters, resulting in a comprehensive analysis of a multitude of specific topics."

    Who should buy this spectacular new text?

  • Plant biologists and scientists in related fields
  • Professors in departments of plant biology, plant biochemistry, plant physiology, and related fields
  • Graduate and upper-level undergraduate students of plant biology
  • Researchers in the pharmaceutical, biotechnology, and agribusiness industries

    A CD-ROM of all illustrative matter in the book is available separately. ... Read more

    Reviews (3)

    3-0 out of 5 stars Explanations not very comprehensive
    The text covers a wide variety of plant molecular biology which is convienent. However the explanations are often very vague and do not connect with each other. When reading a paragraph you are often left with unanswered questions and the next paragraph may not connect with the previous paragraph at all. Not at all recommended for the beginner or undergraduate.

    5-0 out of 5 stars Comprehensive
    This text book is astoundingly comprehensive. It covers all aspects of plant biochemistry and is written for the advanced undergraduate or graduate student. Great resource as reference material.

    5-0 out of 5 stars A Comprehensive and Generously Ilustrated Textbook
    It is a nice comprehensive textbook, which can satisfy both who looks for theoretical information and who are working on advance plant molecular techniques in research laboratory! ... Read more


  • 11. Biochemistry & Molecular Biology of Plants
    list price: $213.00
    our price: $213.00
    (price subject to change: see help)
    Asin: 0943088372
    Catlog: Book (2002-05-10)
    Publisher: John Wiley & Sons
    Sales Rank: 550219
    Average Customer Review: 4.33 out of 5 stars
    US | Canada | United Kingdom | Germany | France | Japan

    Book Description

    Biochemistry Molecular Biology of Plants is a major contribution to the plant sciences literature, superbly edited by three distinguished scientists, Bob B. Buchanan, Wilhelm Gruissem, and Russell L. Jones, with contributions from more than 50 world-renowned scientists. With over 1,400 pages, 1,100 full-colour original drawings and 500 photographs this work qualifies, in the words of the Science reviewer, as:

    "an essential reference for practicing plant biologists and for the increasing number of scientists from other disciplines who are entering the field of plant biology. To exploit fully the wealth of new information provided by the genome projects and to integrate the metabolic, regulatory, and signal transduction pathways of complex organisms, biologists will require a solid command of biochemistry and physiology. For this reason, the publication of Biochemistry Molecular Biology of Plants could not have come at a more opportune and auspicious time."

    This book is meticulously organised and richly illustrated, useful both for teaching and for reference. The multi-authored work provides a contemporary view of its subject, including molecular biology, cell biology, and plant physiology, integrated around the themes of:

    • compartmentation
    • cell reproduction
    • energetics
    • metabolism
    • development
    Read the words of the reviewer in CELL:

    "The great strength of this book is that it has integrated its three major components (molecular biology, cell biology, and plant biochemistry) in each of the 24 chapters, resulting in a comprehensive analysis of a multitude of specific topics."

    Who should buy this spectacular new text?

  • Plant biologists and scientists in related fields
  • Professors in departments of plant biology, plant biochemistry, plant physiology, and related fields
  • Graduate and upper-level undergraduate students of plant biology
  • Researchers in the pharmaceutical, biotechnology, and agribusiness industries

    A CD-ROM of all illustrative matter in the book is available separately. ... Read more

    Reviews (3)

    3-0 out of 5 stars Explanations not very comprehensive
    The text covers a wide variety of plant molecular biology which is convienent. However the explanations are often very vague and do not connect with each other. When reading a paragraph you are often left with unanswered questions and the next paragraph may not connect with the previous paragraph at all. Not at all recommended for the beginner or undergraduate.

    5-0 out of 5 stars Comprehensive
    This text book is astoundingly comprehensive. It covers all aspects of plant biochemistry and is written for the advanced undergraduate or graduate student. Great resource as reference material.

    5-0 out of 5 stars A Comprehensive and Generously Ilustrated Textbook
    It is a nice comprehensive textbook, which can satisfy both who looks for theoretical information and who are working on advance plant molecular techniques in research laboratory! ... Read more


  • 12. Medical Instrumentation : Application and Design
    list price: $114.95
    our price: $114.95
    (price subject to change: see help)
    Asin: 0471153680
    Catlog: Book (1997-08-11)
    Publisher: Wiley
    Sales Rank: 227192
    Average Customer Review: 3.75 out of 5 stars
    US | Canada | United Kingdom | Germany | France | Japan

    Book Description

    This well-established text describes the principles, applications and design of the medical instrumentation most commonly used in hospitals. Because equipment changes with time, the authors stress fundamental principles of operation and general types of equipment. They avoid detailed descriptions and photographs of specific models. Design principles are emphasized so that a scientist with only some background in electronics can gain enough information to design instruments that may not be commercially available. Since biomedical engineering is an interdisciplinary field, the authors have provided varied healthcare industry applications for each type of instrument. ... Read more

    Reviews (4)

    4-0 out of 5 stars Electronic Medical Instrumentation
    As a coursebook, I found 'Medical Instrumentation' to be a sound survey of electrical medical diagnostic instrumentation. The book does review electrical therapeutic medical instrumentation; however, it's coverage is not as thorough.

    This is an excellent resource for engineers planning to specialize in medical device design.

    A good understanding of physiology is necessary to fully utilize the Medical Instrumentation text. If you have little medical background, I recommend Review of Medical Physiology (by William Ganong) as a companion.

    3-0 out of 5 stars Could be More Simple
    Explains dynamic characteristics of circuits very well. It has a ton of information - which can be too much. If you are just starting out in a course on instrumentation, I would recommend, "Principles of Bioinstrumentation" by Normann. His book is much simpler. Ideally, you should get both,..., it depends what level you are at (as a 4th year bioengineering student, I preferred the simple version...)

    5-0 out of 5 stars very good
    This book is very good about medical devices and application

    3-0 out of 5 stars The content is almost identical to the second edition
    It was with great enthusiasm that we ordered the 3rd edition of Professor's Webster big hit. With all my respects for Professor Webster, I was personally disapointed to observe that this edition has almost the same content as the second one. Maybe it is worth mentioning that I have adopted this text for my bioinstrumentation course from the very first edition. It is amazing that some of the very good and recent works done by Prof. Webster's team of engineers and students was not at all included. Even the references are almost the same as the second edition. As the second edition had really something to say compared to the first one, the natural expectation was to see a 3rd edition much more elaborated in terms of novelties in the field. The amount of new material put into this edition seems not to justify the publication of the 3rd edition. ... Read more


    13. Field Methods in Archaeology
    by ThomasHester, HarryShafer, Kenneth L. Feder
    list price: $76.25
    our price: $76.25
    (price subject to change: see help)
    Asin: 1559347996
    Catlog: Book (1997-01-31)
    Publisher: McGraw-Hill Humanities/Social Sciences/Languages
    Sales Rank: 206415
    Average Customer Review: 3.38 out of 5 stars
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    Book Description

    This highly regarded comprehensive guide provides an up-to-date overview of the variety of methods used in field archaeology, from research design to excavation strategies to conservation of artifacts and record-keeping. The contributors to the volume bring a wealth of expertise on diverse subjects and offer practical advice on their areas of special interest. ... Read more

    Reviews (8)

    5-0 out of 5 stars Good book for a student
    This is an excellent book for a student of archaeological methods. If you are looking for light reading, as some of the earlier reviews must have been, then look somewhere else.

    5-0 out of 5 stars Fantastic Book
    Fantastic book! Very clear and very comprehensive. If you are serious about archaeology, you'll enjoy this book. If you're a hobbyist or have comprehension issues, you might not enjoy it. Highly recommended.

    5-0 out of 5 stars An archaeological field school in a book.
    This is a comprehensive text book, not of the "Archaeology for Dummies" variety. More than a couple universities use this book as their standard text for senior level courses in archaeological field methods. Be prepared to learn rather than entertained...it's a serious work. As for the writing style, most text books could stand to be re-written by some best-selling author, but had to give this one five stars just to bring its score up from the absurd two and a half it is currently rated at.

    4-0 out of 5 stars Great book for people interested in learning on own time.
    As a person interested in learning more about archaeology field methods, I found this book had good explanations of some very puzzling processes. It also makes a great textbook and was used to prepare students for a field school by professors at UT Dallas. Good book - but you may have to read it over a couple of times in order to fully grasp all the knowledge presented.

    4-0 out of 5 stars Some comments from the senior author
    The three recent comments on FIELD METHODS, 7th ed. need some clarification. Yes, the book is long, very long. I didn't know we had any statistics in it (reviewer #1)! It is not comparable to Joukowsky, as her book, like our 6th ed., Hester, et al. l975, is now badly out of date. The 7th ed., l997, is designed as (l) a text, especially for field schools (2) a reference on contemporary approaches to field archaeology. It is not a trade book, especially since Mayfield does not discount to bookstores. The long-winded aspect comes from an effort to review contemporary archaeology, which is changing rapidly and covers a broad area of inquiry. The academic review cards received by Mayfield after publication were overwhelmingly positive. Thus, the book appeals largely to professionals and active avocational archaeologists. It is not a "light read" on the glorious discoveries of archaeology. ... Read more


    14. Mechanics of the Cell
    by David Boal
    list price: $55.00
    our price: $55.00
    (price subject to change: see help)
    Asin: 0521796814
    Catlog: Book (2002-01-15)
    Publisher: Cambridge University Press
    Sales Rank: 409098
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    Book Description

    Biological physics, the application of physics to provide an understanding of biological phenomenas, is a burgeoning, new inter-disciplinary subject. This text explores the physics behind the architecture of a cell's envelope and internal scaffolding, as well as the properties of its soft components. The analysis is performed within a consistent mathematical framework, although readers can navigate from the introductory material to biological applications without working through the intervening mathematics. The book includes applications and extensions handled through problems at the end of each chapter. This text is aimed at senior undergraduates and graduate students in science and biomedical engineering. ... Read more


    15. Monte Carlo Methods in Financial Engineering (Applications of Mathematics)
    by Paul Glasserman
    list price: $69.95
    our price: $55.96
    (price subject to change: see help)
    Asin: 0387004513
    Catlog: Book (2003-10-01)
    Publisher: Springer-Verlag
    Sales Rank: 23723
    Average Customer Review: 3.8 out of 5 stars
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    Book Description

    Monte Carlo simulation has become an essential tool in the pricing of derivative securities and in risk management. These applications have, in turn, stimulated research into new Monte Carlo methods and renewed interest in some older techniques.

    This book develops the use of Monte Carlo methods in finance and it also uses simulation as a vehicle for presenting models and ideas from financial engineering.It divides roughly into three parts. The first part develops the fundamentals of Monte Carlo methods, the foundations of derivatives pricing, and the implementation of several of the most important models used in financial engineering.The next part describes techniques for improving simulation accuracy and efficiency.The final third of the book addresses special topics: estimating price sensitivities, valuing American options, and measuring market risk and credit risk in financial portfolios.

    The most important prerequisite is familiarity with the mathematical tools used to specify and analyze continuous-time models in finance, in particular the key ideas of stochastic calculus. Prior exposure to the basic principles of option pricing is useful but not essential.

    The book is aimed at graduate students in financial engineering, researchers in Monte Carlo simulation, and practitioners implementing models in industry. ... Read more

    Reviews (5)

    2-0 out of 5 stars Mathematically disappointing book
    Don't be fooled by the name of the Springer series where this book appeared: if you are looking for a nice list of examples and applications, then this book may be ok, but otherwise, this is not the place to look for proofs and rigorous results.

    5-0 out of 5 stars Excellent Read
    Very well written book , all you need to know about MC Methods.
    If you want to buy one book buy this one, if you have deep pockets then may be you should get the Peter Jaeckal book along with this. There is another introductory book on Simulation by Sheldon Ross.

    5-0 out of 5 stars a great buy
    This is the best book I've read in the last year on mathematical finance. It is a tightly focussed text on Monte Carlo methods no more no less. So you won't find things like day count fracs because that's not what it's about.

    Glasserman is a true expert on the topic. My highlight was the chapter on variance reduction where the vast amount of detailed knowledge taught me a lot, although I implement monte carlo pricing models on a day to day basis.

    2-0 out of 5 stars Compared to the best, this is average.
    This book has a good explanation of Monte Carlo methods, but so do many others. Given that the focus of this book is interest rate models, I must compare it with the best in the field, and this book falls short. The definitive encyclopedia is "Interest Rate Modelling: Financial Engineering" by Jessica James and Nick Webber. Ms. James's Ph.D. in physics and on-line experience shows through in the sound explanation and application of theory.

    Glasserman falls down in the actual applications, since some of the key real-world ingredients such as day counts and quirks of the market are missing.

    "Interest Rate Modelling" covers these features and more. It also reviews hundreds of publications. All the methods for term structure modeling are clearly discussed, and the authors made improvements on some of the original works. "Interest Rate Modelling" still the standard for serious professionals, and while this book is good, compared to a superior work it only merits 2.5 stars.

    5-0 out of 5 stars Monte Carlo applications and much more!
    I just got this book and start reading a few topics of interest like Risk Management. The book covers a lot of material in various financial products (heavy on interest rate products) and disciplines and does a fairly detailed job. It would have been great to have expanded the book to cover some areas more in depth (credit and operational risk), but otherwise this book is pretty comprehensive in terms of Monte Carlo applications. The book also has a nice appendix section that covers stochastic calculus and other topics. I took a course by Professor Glasserman at Columbia University ages ago and the book as well as the course delivers. This book is an excellent reference for any practitioner or academic alike (highly recommended). If you had to choose, I also think this book is better than the Peter Jaeckel's book on Monte Carlo. Enjoy... ... Read more


    16. Biocatalysis
    by Andreas SebastianBommarius, Bettina R. Riebel
    list price: $175.00
    our price: $160.66
    (price subject to change: see help)
    Asin: 3527303448
    Catlog: Book (2004-03-26)
    Publisher: Wiley-VCH
    Sales Rank: 464932
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    Book Description

    This book not only covers reactions, products and processes with and from biological catalysts, but also the process of designing and improving such biocatalysts, taking into account all recent insights.
    A unique feature is that the fields of organic chemistry, biology and bioengineering receive equal attention, such that practitioners and students from all three areas are addressed.
    ... Read more


    17. Basic Biomechanics with Dynamic Human CD and PowerWeb/OLC Bind-in Passcard
    by Susan J Hall, Susan Hall
    list price: $97.81
    our price: $97.81
    (price subject to change: see help)
    Asin: 0072552417
    Catlog: Book (2002-06-26)
    Publisher: McGraw-Hill Humanities/Social Sciences/Languages
    Sales Rank: 62357
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    Book Description

    Basic Biomechanics provides an introduction to biomechanics using the latest findings from the research literature to support and exemplify the concepts presented.Quantitativeas well as qualitative examples of problems illustrate biomechanical principles. Quantitative aspects are presented in a manageable, progressive fashion to make biomechanical principles accessible to all students, regardless of their mathematical skills. ... Read more


    18. More Than Human : Embracing the Promise of Biological Enhancement
    by Ramez Naam
    list price: $24.95
    our price: $16.47
    (price subject to change: see help)
    Asin: 0767918436
    Catlog: Book (2005-03-08)
    Publisher: Broadway
    Sales Rank: 12069
    Average Customer Review: 5.0 out of 5 stars
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    Reviews (5)

    4-0 out of 5 stars Realistic and optimistic
    In the last few years there have been a number of books that have served as excellent apologies for the ongoing and very rapid technological developments. The authors of these books have their own beliefs as to the actual rate of technological progress, but they are uniform in their unrelenting optimism about this progress. This is indeed refreshing, considering that most authors that discuss scientific and technological development seem to have one singular goal: to instill anxiety and foreboding in their readers. The author of this book will have none of that, and has written a book that projects a future that is both believable and scientifically realistic. In addition, the author does not hesitate to speculate, but is always careful to note when his speculations begin and end. He also points out the risks that are involved in human modification, and exhibits caution when it is appropriate.

    One particular topic that the author addresses early on is gene therapy, and considering the hit that gene therapy has taken in the press recently, this is an appropriate choice of topics. It would be unwise to dismiss the viability of gene therapy so early in the game, and the biotech industry needs to be more aggressive in its development. The author discusses some of the applications of gene therapy, including that of the isolation of the growth hormone erythropoietin (EPO) in order to treat anemia. EPO gene therapy could be used by athletes to boost performance, but the author cautions that EPO is probably responsible for the deaths of several athletes in the early 1990's. He also describes alternative strategies using gene promoters, that will allow the control of the EPO levels, and also "hybrid" approaches that involve both the taking of pills and gene therapy. Also discussed are gene therapies for cosmetic enhancement, for curing baldness, and for curing Alzheimer's disease. Gene therapy for the latter involves the modification of neurons in order that they have extra copies of the gene responsible for production of NGF (nerve growth factor).

    Some laboratory evidence involving laboratory mice indicates that NGF gene therapy could improve their learning and memory. The author points out one experiment where extra levels of NGF enabled mice to navigate a maze about 60 percent faster than normal mice. He also discusses research where mice were genetically engineered to have extra copies of the NR2B gene, which produces proteins that are needed for the NMDA receptors in the hippocampus. These mice learned things more quickly at any age than normal mice. The downside of this genetic engineering is that the mice also "unlearned" more quickly, and seemed to be more susceptible to pain than ordinary mice.

    Another unique feature of this book that sets it apart from other apologies for enhancement technologies is the inclusion of statistical evidence for many of its assertions. The reader will find bar graphs, references to pertinent statistical studies in the literature, and other graphs as appropriate. Particularly interesting is the graph on worldwide life expectancy, since it indicates that life expectancy at later age has not risen much in the last one hundred years. The author then proceeds to give a fascinating account of the research that has been done in life extension in the last few years. Some of this research involved the changing of a single gene, which for the case of the nematode worm resulted in the tripling of its life span. Even though his discussion is fairly short, the author gives enough to motivate the reader to search for more in-depth discussion of the research in this very exciting area. The possibility of increasing human life spans by decades or more will of course raise the interest of the majority of people. The author believes that therapies that can increase human life span will enter into human trials within the next decade. This is a very optimistic projection considering the current perceptions of the FDA and the pharmaceutical industry as a whole.

    Readers who are impatient to get on with the genetic engineering of humans will have to wait a little longer. As the author reminds us, the germline genetic engineering of a human embryo has not been attempted as of yet. The gene therapy for Ashanti DeSilva was `somatic' gene therapy, and could not be passed on to her children. The author though mentions a procedure that would blur the distinction between germline genetic engineering and somatic gene therapy. It involves in utero gene therapy, and is done while the fetus is still in the mother's womb. Such a technique was never carried out, due to regulatory restrictions, but the author gives several reasons why it could be viable. Genetic diseases like Tay-Sachs, cystic fibrosis, congenital heart problems could be eliminated he says by this technique. The author points out, interestingly, that 59 percent of the American population approves of the use of genetic engineering to eliminate disease from the unborn. It is actually surprising, at least to this reviewer, that this figure is so high, given the anxiety about genetic engineering in general, even in areas as "trivial" ethically as genetically modified crops. In addition, and this is most refreshing to read, the number of Americans who approve of genetic engineering to create desired traits in children went from 10 percent in 1994 to 20 percent in 2002, according to a study quoted in the book. This is a promising trend, and gives one hope that the population as a whole will eventually appreciate the ethical soundness of using genetic engineering.

    The author also addresses the controversy on human reproductive cloning, noting correctly that it is not safe to perform today, but supporting its use when safety concerns have been overcome. Reproductive cloning will hopefully become routine in this century, and human clones will enjoy the rights that all humans have. Banning reproductive cloning is not necessary, the author argues. Clones will be ordinary people, like the rest of us.

    5-0 out of 5 stars Lucid and wonder inducing, M.T.H. is a must read!
    In More Than Human, Naam's writing is a compelling look at our probable future. Through genetic techniques, drugs, computer and robotic technology, we will have many avenues to enhance our minds and bodies.

    Naam presents a wonderful and engaging survey of current, cutting-edge scientific research across various fields including medicine, genetics, biology, robotics, and computers. The central theme, of course, is that all of these endeavors involve improving the human body and/or mind.

    Unfortunately, many oppose the idea of enhancing our minds and bettering our bodies. They argue that such desires are "unnatural" and go against what it means to be human. They further believe that decisions on the future technologies of bio-enhancement should be made by a select few. Naam convincingly argues that the desire to improve and enhance ourselves is in fact a central trait that defines our humanity. Indeed, nothing could be more "natural" than the interest in improving ones abilities, including the ability to have better, longer, and healthier lives. Naam also demonstrates how the governance of these issues by an elite cadre of political appointees is ultimately more harmful than allowing the billions of inviduals who will make use of these bio-enhancements to choose for themselves.

    In sum, Naam writes clearly and with infectious excitementabout topics that could easily be confused as science fiction. The great wonder however, as Naam is able to show us, is that these topics are very much science fact. We can not avoid what bio-enhancement will do to us as individuals and to our society. We should allow our enthusiasm and optimism to fully accept the inevitable changes that are coming, so that with full understanding we can properly integrate them into our lives.

    5-0 out of 5 stars A rare voice: rigorous and accessible
    Naam describes recent scientific advances with the rigor of an academic researcher, but in terms that you don't need a PhD to understand.He also does an insightful job of relating recent breakthroughs to historic scientific firsts.For example, he makes a credible case that someday choosing the genes of your children will be just as common and non-creepy as in-vitro fertilization is today.He covers a wide range of topics, describing science that could lead to 150 year lifespans or being able to google things just by thinking about them.I was hoping for a bit more about nanotechnology, but maybe it's still a bit early for that.;)

    He explains how these technologies can be helpful to society if embraced.The more compelling argument is how frightening they could be if restricted.He draws astute connections to the rise of already common technologies like reading or antibiotics.Even if you don't agree with everything he believes, his position is well argued, and insightful.

    Most importantly, from a crowd screaming in panic about a changing world, Naam's perspective stands out as calm, optimistic, logical and caring.

    5-0 out of 5 stars Why I Wrote This Book
    In 1999, a friend suggested to me that within a few decades we'd have Matrix-esque implants in our brains that would, among other things, allow us to interact in a completely believable virtual reality and beam our thoughts instantly to one another.I pooh-pooh'ed the idea.The brain and body are much too complex to manipulate in that way, or so I thought.

    That same year a scientist named Phil Kennedy in Atlanta implanted an electrode into the brain of a paralyzed patient named Johnny Ray - a stroke victim who was completely unable to move, speak, or feed himself.The electrode monitored the activity of just a few neurons inside the patients brain. But through it Johnny was able to learn to control a computer - moving a cursor around on a screen and typing out messages.

    Later that year, Joe Tsien at Princeton made the cover of Time Magazine with his Doogie mice - genetically engineered mice that could learn at astounding speeds, up to five times as fast as genetically normal mice.

    And that year is also when I learned of the pioneering longevity research of scientists like Tom Johnston at Colorado, who had genetically altered nematode worms to more than double their lifespan and preserve youthful health into old age.

    Suddenly, it seemed, science was resembling science fiction.

    At the same time, there are a number of voices raised in concern over these technologies.What does it mean to extend our lives, boost our mental abilities, or integrate our minds with computers?Would we still be human?What would happen to society?To equality?To the meaning of life?

    I wrote this book to cover these two, interrelated topics:

    1)The science of human enhancement - what's actually happening in the labs and what that could lead to in the near future.

    2)The ethics, social consequences, and policy challenges of human enhancement.Basically, what we should or shouldn't do with this technology.

    More Than Human is an optimistic book, but it's a cautious optimism.Along the way it looks at issues like the effect of longer lives on overpopulation, on socio-economic stratification and whether these technologies would help the rich pull further away from the poor, and at issues like human identity, and whether we could even call ourselves human after changing ourselves in such ways.

    It's not a utopian book.There can be no doubt that using biotechnology to alter the human mind, body, and lifespan will lead to problems.But the conclusion I come to in the book is that these technologies will solve more problems than they create.And that the alternative - to prohibit their use - will create many more problems than it will solve.

    You can read more at http://www.morethanhuman.org/

    I hope you enjoy the book.

    5-0 out of 5 stars Excellent though too optimistic account of humanity's future
    Naam touches on many of the most crucial milestones in the most optimistic visions of humanity's future: genetic medicine, drug therapies, human cloning, and cybernetic enhancement to name a few. He does so in a way that is scientifically rigorous without becoming mired in the details in a way that would make the account difficult to read for those without a scientific background.

    Some readers may be put off by the directness with which he approaches issues which are very controversial, but these technologies are already in use and Naam makes a persuasive argument that, like it or not, the rest of them will be in regular use sooner or later.

    While I am personally skeptical of the rose colored glasses through which Naam looks at the future, this book is an undeniably excellent introduction to our technological future and is an enjoyable read at that. ... Read more


    19. Biological Sequence Analysis : Probabilistic Models of Proteins and Nucleic Acids
    by Richard Durbin, Sean R. Eddy, Anders Krogh, Graeme Mitchison
    list price: $45.00
    our price: $34.65
    (price subject to change: see help)
    Asin: 0521629713
    Catlog: Book (1999-07-01)
    Publisher: Cambridge University Press
    Sales Rank: 62111
    Average Customer Review: 4.73 out of 5 stars
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    Book Description

    Probablistic models are becoming increasingly important in analyzing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project.For example, hidden Markov models are used for analyzing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it is accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time presents the state of the art in this new and important field. ... Read more

    Reviews (11)

    5-0 out of 5 stars Excellent overview of probabilistic computational biology
    This book is a very well written overview to hidden Markov models and context-free grammar methods in computational biology. The authors have written a book that is useful to both biologists and mathematicians. Biologists with a background in probability theory equivalent to a senior-level course should be able to follow along without any trouble. The approach the author's take in the book is very intuitive and they motivate the concepts with elementary examples before moving on to the more abstract definitions. Exercises also abound in the book, and they are straightforward enough to work out, and should be if one desires an in-depth understanding of the main text. In addition, there is a software package called HMMER, developed by one of the authors (Eddy) that is in the public domain and can be downloaded from the Internet. The package specifically uses hidden Markov models to perform sequence analysis using the methods outlined in the book.

    Probabilistic modeling has been applied to many different areas, including speech recognition, network performance analysis, and computational radiology. An overview of probabilistic modeling is given in the first chapter, and the authors effectively introduce the concepts without heavy abstract formalism, which for completeness they delegate to the last chapter of the book. Bayesian parameter estimation is introduced as well as maximum likelihood estimation. The authors take a pragmatic attitude in the utility of these different approaches, with both being developed in the book.

    This is followed by a treatment of pairwise alignment in Chapter Two, which begins with substitution matrices. They point out, via some exercises, the role of physics in influencing particular alignments (hydrophobicity for example). Global alignment via the Gotoh algorithm and local alignment via the Smith-Waterman algorithm, are both discussed very effectively. Finite state machines with accompanying diagrams are used to discuss dynamic programming approaches to sequence alignment. The BLAST and FASTA packages are briefly discussed, along with the PAM and BLOSUM matrices.

    Hidden Markov models are treated thoroughly in the next chapter with the Viterbi and Baum-Welch algorithms playing the central role. HIdden Markov models are then used in Chapter 4 for pairwise alignment. State diagrams are again used very effectively to illustrate the relevant ideas. Profile hidden Markov models which, according to the authors are the most popular application of hidden Markov models, are treated in detail in the next chapter. A very surprising application of Voronoi diagrams from computational geometry to weighting training sequences is given.

    Several different approaches, such as Barton-Sternberg, CLUSTALW, Feng-Doolittle, MSA, simulated annealing, and Gibbs sampling are applied to multiple sequence alignment methods in Chapter 6. It is very well written, with the only disappointment being that only one exercise is given in the entire chapter. Phylogenetic trees are covered in Chapter 7, with emphasis placed on tree building algorithms using parsimony. The next chapter discusses the same topic from a probabilistic perspective. This to me was the most interesting part of the book as it connects the sequence alignment algorithms with evolutionary models.

    The authors switch gears starting with the next chapter on transformational grammars. It is intriguing to see how concepts used in compiler construction can be generalized to the probabilistic case and then applied to computational biology. The PROSITE database is given as an example of the application of regular grammars to sequence matching. This chapter is fascinating reading, and there are some straightforward exercises illustrating the main points.

    The last chapter covers RNA structure analysis, which introduces the concept of a pseudoknot. These are not to be confused with the usual knot constructions that can be applied to the topology of DNA, but instead result from the existence of non-nested base pairs in RNA sequences. The authors discuss many other techniques used in RNA sequence analysis and take care to point out which ones are more practical from a computational point of view. Surprisingly, genetic algorithms and algorithms based on Monte Carlo sampling are not discussed in the book, but the authors do give references for the interested reader.

    The best attribute of this book is that the authors take a pragmatic point of view of how mathematics can be applied to problems in computational biology. They are not dogmatic about any particular approach, but instead fit the algorithm to the problem at hand.

    5-0 out of 5 stars Brief and clear
    I keep coming back to this book for its readable, applicable summaries of basic algorithms.

    One chapter covers the basics of dynamic programming for string matching: a staple of bioinformatics computing. The authors come back to it a number of times as they introduce new variations on the string-matching theme. They give about the clearest description of the Needleman-Wunsch and basic variants (including Smith-Waterman) of any book I know.

    The bulk of the book is devoted to Hidden Markov Models (HMMs), as one might have guessed in a book with Eddy as co-author. It covers the basics of model construction, motif finding, and various uses for decoding. Again, it covers all the basics so clearly you'll want to start coding as soon as you read it.

    The later sections of the book cover phylogeny and tree building, along with the relationships to multiple alignment. Good, solid, clear writing prepares the reader for texts that may be more specialized, but possibly less transparent.

    The next-to-last chapter, on RNA folding, is weaker than the ones before, in my opinion. It ties to the other chapters reasonably well in terms of algorithms, but I don't think it does justice to the thermodynamic models of RNA folding. If there is any weakness in this chapter, though, it does not detract from the strengths elsewhere.

    The final chapter, the "background on probability", is the one that I think needs the most support. If you don't already understand its topics, I doubt that this will help very much. (If you do understand them, you won 't need the help.) There's nothing inherently tricky about probability, but individual distributions carry many assumptions, and I did not see those spelled out well.

    This shouldn't be the only book in your bioinformatics library. If you really want algorithms, though, it's a good book to have in the collection and one you'll keep coming back to.

    3-0 out of 5 stars Good bargain, but...
    not suffciently precise for being an academic textbook. The definitions are sometimes incomplete, correctness proofs are missing, some exercises are incorrect. On the positive side, it does cover important topics, and brings good examples to illustrate main concepts and algorithms (which partially compemsates for the lack of precisenss).

    5-0 out of 5 stars Simply Excellent!
    This book explained topics I was interested in above my personal expectations. All the mathematics and probabilistic models were explained in detail with a practical approach. I was even able to refine some of those models for specific needs without much previous experience nor knowledge. I highly recommend this book, it is one of the best I ever read.

    5-0 out of 5 stars Don't let the title mislead you.
    Don't let the title fool you. This book is a great if you'd like to understand the algorithms used in any type of sequence analysis, for example speech recognition, speech synthesis, and natural language understanding.

    I used this book for a bioinformatics class. The instructor's notes were basically a rehash of the textbook. This didn't bother me as there really is no way to improve on what's already in the text. Explanations of the different ways to use HMMs made it easy to write the genefinder we did for our final programming project.

    I've also written natural language processing software (for text and speech) and I've found this book to be a great reference for probabilistic language modeling algorithms. The material is similar to that found in Jurafsky and Martin, or Manning and Schutz, but the presentation in DEKM provides more insight into how the algorithms work. This should come as no surprise, as the human genome project is perhaps the most successful artificial intelligence project ever undertaken and the authors were instrumental in creating the software used by the HGP.

    The book by Gusfield is also great for sequence analysis, but there the emphasis is on deterministic modeling, which has it's place if one can't make a probabilistic sequence model.

    Mining databases of text, image, and sound sequences is becoming more important as more data is available on the web. Books like DEKM are valuable algorithm resources for extracting knowledge all sorts of sequence data. ... Read more


    20. Biodiesel: Growing A New Energy Economy
    by Greg Pahl
    list price: $18.00
    our price: $12.24
    (price subject to change: see help)
    Asin: 1931498652
    Catlog: Book (2005-01-15)
    Publisher: Chelsea Green Publishing Company
    Sales Rank: 109308
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    Book Description

    Has world oil ouptut peaked? Recent price spikes and dwindling reserves have spurred fears that we are fast approaching the critical tipping point that will trigger severe global economic depression, political instability, and human suffering.

    Today 95 percent of global oil is consumed for transportation, and other alternatives are distant possibilities at best. We need a solution now, one that will pave the way to a saner, more sustainable energy future without massive reinvestments in infrastructure and technology transfer. We need biodiesel.

    A crop-derived liquid fuel, biodiesel can be made from a wide range of renewable, locally grown plant sources--even from recycled cooking oils or animal fats. The technology is simple and available today, and the benefits of biodiesel are enormous, as both a cleaner-burning vehicle fuel and a source for residential or commercial heating.

    Greg Pahl’s essential new book explores the history and technology of biodiesel, its current use around the world, and its exciting potential in the United States and beyond. While biodiesel is not the answer to all our energy problems, it is an important step in the long overdue process of weaning ourselves from fossil fuels. ... Read more


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