Reviews (1)

A classic reference
Ingle and Crouch have done a wonderful job in putting together a true reference text.This is a must have text for analytical chemists who need to have a concise treatment of spectrochemical analysis.They have done awonderful job in intergrating theory with practice for a wide variety ofanalytical techniques.This book was indespensible as a graduate studentin the late 80's and still comes in handy today! ... Read more

Book Description

This text is designed for the one-term Quantitative Analysis/Analytical Chemisty course for students majoring in Chemistry and related fields.  It deals with principles and techniques of quantitative analysis. Examples of analytical techniques are drawn from such areas as life sciences, clinical chemistry, air and water pollution, and industrial analyses. The Sixth Edition is extensively revised and updated with a more modern flavor and a new, two-color design. ... Read more

Book Description

Breakthroughs in combinatorial chemistry and molecular biology, as well as an overall industry trend toward accelerated development, mean the rate of sample generation now far exceeds the rate of sample analysis in the pursuit of producing new and better pharmaceuticals. LC/MS is an analytical tool that helps the researcher identify the most promising sample early in the selection process, effectively creating a shortcut to finding new drugs. This book is the first to describe LC/MS applications within the context of drug development, including the discovery, preclinical, clinical, and manufacturing phases.
In addition to the thorough technical analysis of this tool, LC/MS Applications in Drug Development provides perspective on the significant changes in strategies for pharmaceutical analysis. A process overview of drug development from an analytical point of view is provided along with essential data required to successfully bring a drug to market. The incorporation of LC/MS is illustrated from target to product. Chapters pertaining to the discovery process itself include:

-Proteomics
-Glycoprotein Mapping
-Natural Products Dereplication
-Lead Identification Screening
-Open-Access LC/MS
-In Vitro Drug Screening

Written for both the analytical chemist who uses LC/MS applications and the pharmaceutical scientist who works with the drugs they produce, LC/MS Applications in Drug Development is the premier reference on the subject. ... Read more

Book Description

The third edition of this highly successful manual is not only a revised text but has been extended to meet the interpretive needs of Raman users as well as those working in the IR region. The result is a uniquely practical, comprehensive and detailed source for spectral interpretation. Combining in one volume, the correlation charts and tables for spectral interpretation for these two complementary techniques, this book will be of great benefit to those using or considering either technique.
In addition to the new Raman coverage the new edition offers:
* new section on macromolecules including synthetic polymers and biomolecules;
* expansion of the section on NIR (near infrared region) to reflect recent growth in this area;
* extended chapter on inorganic compounds including minerals and glasses;
* redrawn and updated charts plus a number of new charts covering data new to this edition.
This new edition will be invaluable in every industrial, university, government and hospital laboratory where infrared (FT-IR) and Raman spectral data need to be analysed. ... Read more

Book Description

Practical Environmental Analysis is supplemented by theoretical material explaining, amongst other concepts, the principles behind each method and the importance of various pollutants. Also included are suggestions for projects and example calculations. ... Read more

Book Description

One of the greatest challenges facing chemists and chemical educators today is conveying the central importance and relevance of chemistry to students and society at large. The new edition of Chemistry Connections highlights the fundamental role of chemical principles in governing our everyday experiences and observations.

Introductory chemistry students and educators as well as laypersons with an inquisitiveness about the world around them will find the book an informative introduction to the context of chemistry in their lives. The book is written in a lively question-and-answer format with presentations in both lay and technical terms.

* Two levels of explanations: general, accessible ones highlight the chemical essence of the phenomenon; and technical ones using chemical principles provide more in-depth interpretation
* Indexing of questions according to key principles or terms enhances instructional use
* Figures and 3-D chemical structures illustrate the chemical concepts presented
* References to related World Wide Web sites for further exploration provide inexpensive and convient access to related information.
* Color plates enhance connections between specific topics ... Read more

Reviews (4)

An absorbing intermediate to advanced level chemical text
Now in an updated second edition, Chemistry Connections: The Chemical Basis Of Everyday Phenomena is an amazing volume with chapters based around answers to questions such as "What causes an egg to crack if it's boiled too rapidly?"; "Why do carbonated drinks go flat as they warm?"; "Why do lightsticks glow?"; "How does a timed-release medicine work?"; and much, much more. The collaborative effort of Kerry K. Karukstis (Professor of Chemistry, Harvey Mudd College) and Gerald R. Van Hecke (Professor of Chemistry, Harvey Mudd College), Chemistry Connections is an absorbing intermediate to advanced level chemical text that makes learning chemistry a lot of fun in some unique but quite effective ways.

there are better alternatives
Overall this book and is fairly successful in its aim of explaining a selection of everyday chemical phenomena in terms accssible to most people. There are a couple of points which really let it down though.
First, the presentation of the material and the diagrams could be greatly improved. For example, there is a "3-D" structure of EDTA given. In fact, it just seems to be a 2-D Chemdraw diagram pasted in to Chem3D! It gives no sense of how the dispostion of the oxygen and nitrogen atoms allow EDTA to surround the metal centre thus making it an effective metal sequestering agent.
Second, certain sections go in to extraordinary detail concerning the physical chemistry of certain phenomena. Rather complicated equations and diagrams are presented which don't aid the reader in really understanding conceptualising the processe which are described.
Third, annoyingly, temperatures are presented only in Fahrenheit. Hello!? Did the authors not consider that they may have readers outside of the US.....
(...)

Great teacher resource
I found Chemistry Connections very interesting and informative. I am a high school science teacher and I already have a strong background in chemistry. The format presents infomation on each question at multiple levels of sophistication, from introductory information accessible without much knowledge of chemistry to in-depth information on specific molecular structures and interactions. This book would be a great resource for chemistry teachers. My only critisism is that the writing style could be a bit more engaging.

Fascinating without forsaking the science
Chemistry Connections is an excellent, well-written book that I found extremely easy and fun to read. It is a fascinating book for both the layperson and the scientist, presenting explanations of everyday phenomena that all of us have wondered about at one time or another. Things like household cleaners, paper money, seashells, shampoo, and chili pepper are explained on a simplified chemical basis, and then on a more detailed scientific basis. Chemical structures and some reactions are presented, as well as very current references and websites on each topic. This has got to be the most entertaining chemistry book I have every read! ... Read more

Reviews (4)

Great introduction to the basics
This book covers the basics of mass spectra, and how to interpret them by hand. While it doesn't reallly go into modern developments, its certainly a great way to get started thinking about mass spectroscopy in general. Probably most useful for an undergras course in spectroscopy, which is where I first came across it. The nice thing is it has lots of exercises for the reader that are actually alot of fun. Does not, unfortunately, address protein identification and sequencing by mass spec at al, so while I recommend this book as a starting point, a biologically oriented reader would best use this book in conjunction with a more protein-specific reference.

Beginners text
A good introduction to classical mass spectrometry though most of the recent developments in the field are not covered. Most suitable for undergraduates. This edition corrects some of the organizational blunders in earlier forms ; previously a chapter on "Other Ionization Techniques" included sections on negative ions and icrs (?).

Classic Book for Mass Spectrometry
The book is commonly used as a text book on Mass Spectrometry at graduate or undergraduate level. Very nice for organic mass spectrometry. I even read a Chinese version back home.

The examples are good, exercises have answers at the end of book: great for self-practicing. It is too bad that this book does not cover the currently very hot biological mass spectrometry. Anyway this is a book you have to read at least twice if you want to be in the field of mass spectrometry.

A good mass spec reference.
A good reference to have on your desk. Best for graduate students or undergrads. Largely irrelevant for todays working chemist. ... Read more

Book Description

How to design, execute, and interpret experiments for protein sequencing using mass spectrometry

The rapid expansion of searchable protein and DNA databases in recent years has triggered an explosive growth in the application of mass spectrometry to protein sequencing. This timely and authoritative book provides professionals and scientists in biotechnology research with complete coverage of procedures for analyzing protein sequences by mass spectrometry, including step-by-step guidelines for sample preparation, analysis, and data interpretation.

Michael Kinter and Nicholas Sherman present their own high-quality, laboratory-tested protocols for the analysis of a wide variety of samples, demonstrating how to carry out specific experiments and obtain fast, reliable results with a 99uccess rate. Readers will get sufficient experimental detail to apply in their own laboratories, learn about the proper selection and operation of instruments, and gain essential insight into the fundamental principles of mass spectrometry and protein sequencing. Coverage includes:

* Peptide fragmentation and interpretation of product ion spectra
* Basic polyacrylamide gel electrophoresis
* Preparation of protein digests for sequencing experiments
* Mass spectrometric analysis using capillary liquid chromatography
* Techniques for protein identification by database searches
* Characterization of modified peptides using tandem mass spectrometry

And much more ... Read more

Reviews (2)

Broad, thorough introduction
I'm not a bench chemist, but I needed a quick survey of how mass spectroscopy is used in handling proteins and other big biomolecules. This book was it.

Although brief, it is thorough and well-organized. The first two chapters are mostly an introduction. Chapter 1 mostly just states the problem being solved. The next chapter is a brief introduction to older technologies, inclduding chemical techiques and 60s-80s mass spec technique. The next two chapters summarize modern mass spec hardware, then start to show how proteins behave in the environment inside the instrument. That gives the fundamentals of protein sequencing: how the molecules break down, and how the fragments help recreate the molecule. The authors go through a few examples in detail, starting from a mass spectrogram and moving forward to sequence. I was especially impressed by the examples that fail. Mass spec analysis is not a magic wand for producing sequences, it is a deductive process, and can not complete an analysis when clues are missing or ambiguous.

The next three chapters are not about mass spec directly. Instead, they discuss how samples are prepared for analysis. This includes the clearest, most informative description of gel electrophoresis that I've seen, along with features of gel chemistry that do or do not interfere with mass spec measurements. This includes a discussion of protein digests, enzymatically produced fragments, and their place in analysis. I would have liked a little more discussion about combining information from digests produced by different enzymes, but no book can cover everything.

The last three chapters extend the discussion of analysis, working upwards from fragments to complete protein sequences. The three chapters respectively address three topics: using standard internet databases for recognizing fragments of known proteins, using combinations of strategies to analyze novel protein, and using mass spec to identify post-translational modifications. That last one suffers from brevity; perhaps it was only meant to define a problem that deserves a whole book of its own.

Despite its throughness, the authors resist the urge for boggling detail. They present detail up to the point needed for understanding the mechanism and meaning of their topics, then stop. Lots of other writing would benefit from that kind of restraint.

I came away from this book well-informed, and ready to address specific topics in greater detail. That was exactly what I wanted. I recommend this book very highly.

"Protein Sequencing ......" a must to read
Michael Kinter has presented the topic in a scientific yet enjoyable format. I found the information to be extremely interesting and beneficial in my laboratory. Lets face it folks this isn't the easiest nor most interesting topic to write about. Job well done DR. Kinter. I only have one criticism, there should have been more photos and illustrations. Get your copies quick this will no doubt be on the NewYork times best seller list before long. ... Read more

Book Description

This is the first practical reference book that covers state ofthe art analytical methods, instrumentation and data processingtechniques used for high-throughput analysis of new materials incombinatorial chemistry and materials science beyond thepharmaceutical area. This book demonstrates how these techniques areapplied for development of new materials on combinatorial scale andfor scale-up of combinatorial materials leads. The book is written by an international team of contributing authorsand consists of 27 chapters that detail the most recent advances inoptical imaging and spectroscopy; separations and mass spectrometry;sensors and sensor arrays; analysis of mechanical, electrical, andthermal properties; electrochemical analysis; fabrication ofcombinatorial libraries; data management, and scale-up ofcombinatorially discovered materials. High-Throughput Analysisprovides multi-disciplinary practitioners and beginners with atreatment of the principles, methodology, and characteristics ofinstrumentation for high-throughput analysis in order to stimulatefurther research in this rapidly expanding field. Included as a special feature is a CD-ROM that demonstrates the easeof use of the techniques described in the book. ... Read more

Book Description

Since the first edition of this book appeared, computers have come to the aid of modern experimenters and data analysts, bringing with them data analysis techniques that were once beyond the calculational reach of even professional statisticians. Today, scientists in every field have access to the techniques and technology they need to analyze statistical data. All they need is practical guidance on how to use them.Valuable to everyone who produces, uses, or evaluates scientific data, Statistical Techniques for Data Analysis, Second Edition provides straightforward discussion of basic statistical techniques and computer analysis. The purpose, structure, and general principles of the book remain the same as the first edition, but the treatment now includes updates in every chapter, additional topics, and most importantly, an introduction to use of the MINITAB Statistical Software. The presentation of each technique includes motivation and discussion of the statistical analysis, a hand-calculated example, the same example calculated using MINITAB, and discussion of the MINITAB output and conclusions.Highlights of the Second Edition:·Detailed discussion and use of MINITAB in examples complete with code and output·A new chapter addressing proportions, time to event data, and time series data in the metrology setting·Additional material on hypothesis testing·Discussion of critical values·A look at mistakes commonly made in data analysis ... Read more

Reviews (1)

A must have in the engineer's bookshelf
I have used this book in college for my lab courses.In these courses I had to perform statistical analysis of the data.There was one little problem. I did not have formal training in statistics.Well, this book will tell you in a concise way what you need to know about statistical analysis of your data.The topic of uncertainty (Chapter 5) is extremely helful and to the point. If you want to know how to analyze your data accuratelyand don't have much time, this is the book you need to read. ... Read more

Book Description

This book provides a low-level introduction to the fundamentals and practical aspects of ultraviolet/visible spectroscopy, the most commonly used and versatile techniques in analytical chemistry. The second edition includes chapters on the increasingly used new derivative techniques, as well as new examples and applications taken from industry and the academic literature. Easily accesible to the novice. Includes self-assessment questions with responses and numerous examples. ... Read more

Reviews (1)

Excellent book for beginners and intermediates
This book is concise and explains all you need to know in simple english. The excercises help understand the material and they are easy to do. Highly recommended. ... Read more

Book Description

This book presents, for the first time, a unified treatment of the quantum mechanisms of magnetic resonance, including both nuclear magnetic resonance (NMR) and electron spin resonance (ESR). Magnetic resonance is perhaps the most advanced type of spectroscopy and it is applied in biology, chemistry, physics, material science, and medicine. If applied in conjunction with spectroscopy, the imaging version of magnetic resonance has no counterpart in any type of experimental technique.

The authors present explanations and applications from fundamental to advanced levels. Additionally, they pave the way to successfully simulating magnetic resonance phenomena numerically through an accompanying CD-ROM.

The authors present explanations and applications from fundamental to advanced levels

This groundbreaking volume is accompanied by a CD ROM which simulates magnetic resonance phenomena ... Read more

Reviews (1)

folks: the hype is true
I will tell you this: for those people out there who love German people's names, Volker Achim Weberruß's name will not disappoint. And his book... ach, his book-- I will just say this: it lives up to his name.

That is what I will say.

Additionally, I will say that reading this book, you feel ravished by the technical command Volker Achim Weberruß has over his computational domain-- you feel like a young child, in the hands of a brutish master. You feel like a life raft cradled in a tempest-loving sea. You are at his mercy.

Weberruß is the Mayor of Science,, folks.

I will also say this: I was a little disappointed in the appendix, though. Not quite meaty enough, for my taste, and I found several notable ommissions ("hyponautical quadraticism" was mentioned on pages 133 and 411, though the topic was apparently not substantial enough to warrant an appendixical mention). But for that I fault the editor, not Volker Achim Weberruß.

Volker Achim Weberruß is the champion of the history of science of the universe.

Object-Oriented Magnetic Resonance: Yes! ... Read more

Book Description

The first-ever on-the-job guide for the analytical chemist All the conventional wet and instrumental techniques in one exhaustive database. . .along with all the critical data you need to apply them! Save time! Save money! Be more productive! This one-of-a-kind tool gives you fundamental data on: volumetric and gravimetric analysis; chromatographic methods; electronic absorption and luminescence spectroscopy; infrared and Raman spectroscopy; atomic spectroscopy; optical activity and rotary dispersion; refractometry; X-ray methods; radiochemical methods; nuclear magnetic resonance spectroscopy and electron spin resonance; mass spectrometry; electroanalytical methods; magnetic susceptibility; detection and determination of functional groups in organic compounds; methods of determination in water; water analysis; and more! ... Read more

Reviews (1)

A good reference
This book contains many of the important aspects of Analytical Chemistry that would be encountered in the undergraduate level. It would be a good handbook for analytical chemistry but would not be too good as a text as itdoes not contain much detailed principles. ... Read more

Book Description

Includes a Foreword by Dr. James D. Watson, the co-discoverer of the DNA double helix, and Dr. Jan A. Witkowski.

"From the Foreword by Drs. Watson and Witkowski: 'DNA: Forensic and Legal Applications is a comprehensive and invaluable guide to the field, covering topics ranging from collecting samples in the field to presenting the complex results to a jury. We are sure that it will play its part in promoting this most powerful tool in the forensic scientist’s armamentarium.'"

DNA: Forensic and Legal Applications covers the technology and laws related to DNA, as well as the use of DNA evidence in the legal system. This combination of science and law makes it the first comprehensive title of its kind and an appropriate reference for those with both elementary and advanced knowledge of the topic. It draws together in one source information that would previously have required extensive research and reliance on experts to obtain, offering both breadth and depth in a clear style without s acrificing scholarly goals.
With material from both scientific and legal areas, DNA: Forensic and Legal Applications covers the latest advances in technology. It provides an ideal text for forensic scientists and students of forensic science, analytical chemists, lawyers, judges, police officers, and detectives. ... Read more

Book Description

The importance of accurate sample preparation techniques cannot be overstated--meticulous sample preparation is essential.  Often overlooked, it is the midway point where the analytes from the sample matrix are transformed so they are suitable for analysis.  Even the best analytical techniques cannot rectify problems generated by sloppy sample pretreatment.

Devoted entirely to teaching and reinforcing these necessary pretreatment steps, Sample Preparation Techniques in Analytical Chemistry addresses diverse aspects of this important measurement step.  These include:

• State-of-the-art extraction techniques for organic and inorganic analytes
• Sample preparation in biological measurements
• Sample pretreatment in microscopy
• Surface enhancement as a sample preparation tool in Raman and IR spectroscopy
• Sample concentration and clean-up methods
• Quality control steps

Designed to serve as a text in an undergraduate or graduate level curriculum, Sample Preparation Techniques in Analytical Chemistry also provides an invaluable reference tool for analytical chemists in the chemical, biological, pharmaceutical, environmental, and materials sciences. ... Read more

Reviews (1)

Good book for beginners.
A very helpful book for a beginner. It is a very good reference book as well. discusses many practical aspects of operation that I have yet to see in other books. ... Read more