Book Description

Nitric oxide (NO) is a gas that transmits signals in an organism. Signal transmission by a gas that is produced by one cell and which penetrates through membranes and regulates the function of another cell represents an entirely new principle for signaling in biological systems.
NO is a signal molecule of key importance for the cardiovascular system acting as a regulator of blood pressure and as a gatekeeper of blood flow to different organs. NO also exerts a series of other functions, such as acting a signal molecule in the nervous system and as a weapon against infections. NO is present in most living creatures and made by many different types of cells.
NO research has led to new treatments for treating heart as well as lung diseases, shock, and impotence. Scientists are currently testing whether NO can be used to stop the growth of cancerous tumors, since the gas can induce programmed cell death, apoptosis.
This book is the first comprehensive text on nitric oxide to cover all aspects--basic biology, chemistry, pathobiology, effects on various disease states, and therapeutic implications.

Key Features
* Edited by Nobel Laureate Louis J. Ignarro, editor of the Academic Press journal, Nitric Oxide
* Authored by world experts on nitric oxide
* Includes an overview of basic principles of biology and chemical biology
* Covers principles of pathobiology, including the nervous system, cardiovascular function, pulmonary function, and immune defense ... Read more

Book Description

In the decade since the publication of the bestselling first edition, Polymerase Chain Reaction (PCR) technology has been at the forefront of dramatic developments in biochemistry. Many exciting advances have been made in this specialized field of DNA analysis and a large number of commercial kits and additives are now available. There has never been a better time for a comprehensive resource covering the current range of PCR strategies and uses.PCR Technology: Current Innovations, Second Edition is a fundamental reference for scientists new to PCR technology and a source of up-to-date applications for those familiar with the method. It provides theoretical considerations, discussions, and a selection of state-of-the-art techniques for mutation studies, clinical diagnosis, and the detection of food-borne pathogens. The book begins with discussions of the preparation of PCR experiments, followed by examples of analytical PCR divided into qualitative and quantitative applications. The final section explores preparative methods addressing DNA generation for further analysis and in vitro evolution.Featuring detailed presentations of PCR protocols, this volume contains critical information for practitioners in a wide variety of fields, including forensics, molecular biology research, clinical DNA diagnostics, botany, and paleontology. It provides the essential tools for developing innovative approaches in this leading technology of the genomics revolution. ... Read more

Reviews (2)

A nice introduction to structural biology
This book deserves 5 stars on the basis of its color stereo diagrams alone! Well done. I wish I had this book when I was starting out as a graduate student! A very good explanation of structural hierarchy. Plus the book also contains excellent details of structure of proteins belonging to specific families -for ex., antibodies. Even today, for my work, I find it very convenient to look into the book first for some structural information rather than into the PDB databases. And yes, I do have a very good pair of stereo glasses always on hand!

If Frank Lloyd Wright did proteins...
This is truly a monument to the architecture of proteins: a gorgeous tour of the structures that dwell within us. The "frozen music" of biology is clearly presented in beautiful detail. The computer-generated renderings give pause to anyone who wonders what God was up to when She thought about creating life. Proteins, as represented here, are Her finest efforts. Visually stunning is only the most obvious aspect of this amazing introduction to structural genomics (proteinomics): the systematic study of protein structures. This is a serious graduate level textbook.

The text should be considered for any introductory graduate level course in biochemistry. Beginning with sound chemical principles, the text lays a solid foundation for the concepts of secondary and tertiary structure within protein. The author builds a superstructure from which to view the motifs of cofactor binding domains and active sites in enzymes.

Each chapter concludes with exercises, problems and "weblems". The weblems underscore the fact that structural genomics, a branch of bioinformatics, is a hot topic in the biotech arena. The weblems ask the reader to pursue ideas on the world wide web. The author provides the reader with a wealth of websites ranging from browser plug-in software for viewing crystal structures, to sources of those structures, to sequence alignment servers which will allow the student to do real research. Well thought-out, the weblems posed are useful to the student in exploring the topics of each chapter.

The author sticks to protein architecture avidly, issues of how proteins fold or how structure might be predicted from amino acid sequence are presented to the reader. It is a credit to the author that he does not speculate on these very hot research topics. The bibiliography for each chapter is current to mid-2000.

A student using this text will have greater insight and understanding of the literature of protein structure, folding, and prediction of structure. This book would also be a useful reference to the veteran practitioner, summarizing an early 21st century look at this field. ... Read more

Book Description

A best-selling mechanistic organic chemistry text in Germany, this text's translation into English fills a long-existing need for a modern, thorough and accessible treatment of reaction mechanisms for students of organic chemistry at the advanced undergraduate and graduate level. Knowledge of reaction mechanisms is essential to all applied areas of organic chemistry; this text fulfills that need by presenting the right material at the right level. ... Read more

Book Description

This authoritative text begins with an introduction to basic microarray technology. The author then provides clear explanations of the conceptual and theoretical basis of this technology, followed by thorough and multi-disciplinary coverage of modern and emerging applications. The coverageincludes chapters on microarray informatics, gene expression profiling, genetic diagnostics, and novel microarray technologies. ... Read more

Reviews (7)

Highly Recommended
"...the book is highly recommended as an excellent one stop resource on microarray technology" (Proteomics)

Recommended Book
"...a very personal, encyclopedic, diffuse compendium of everything known about microarrays...fun to read...full of information that a working biologist...might be quite interested to learn." (ASM News, Vol. 69, No. 7, 2003)

A grand introduction to a daunting field
As an emerging discipline, Microarray analysis is somewhat overwhelming and this book provides an excellent overview and introduction. While it does not give the reader the ability to perform high level data analysis, it certainly provides the criteria which would be necessary to design one. I personally rather enjoyed the casual and light hearted editaorial handling of what could have been a very dry text. I am an engineer, interested in the techniques of Microarray analysis more than the actual execution, but even I found the book extremely valuable. An excellent introductory and intermediate text. Readable by and valuable to almost anyone with a basic background in and understanfding of the life sciences. Extraordinary and a great addition to any library!

Excellent Foundational Text on Microarray Technology
The Microarray Analysis book by Dr. Mark Schena does an excellent job of taking the reader thru the multiple technologies and science disciplines required to understand and use the power of the microarray. It's interdisciplinary and broad approach allows complete understanding of the field without wasting time on aspects of the field which are sill evolving. It's elegantly written. Chapter 13, which talks about the use of microarrays in genetic screening, testing and diagnostics, is one of Schena's greatest accomplishments, in a historic and socio-economic sense. This contribution alone, makes the book a must read to prepare for the microarray revolution in medicine, agriculture, ecology and bio-threat detection. Strongly recommended reading for anyone seriously interested in Microarrays, be they students, professors expanding their horizons or CEO's hoping to mine microarrays. Hats off to Dr. Mark Schena!

An Excellent Text
"...an excellent text...a valuable reference...If you need to know what microarrays are, how they can be used, how they work, and how you can analyze the data...then this book will provide the insight." (Clinical Chemistry, Vol. 49, No. 6, 2003) ... Read more

Book Description

Covers enzyme kinetics from its most elementary aspects to such modern subjects as steady-state, multi-reactant kinetics and isotope exchange. Offers an understanding of the behavior of enzyme systems and the diagnostic tools used to characterize them and determine kinetic mechanisms. Illustrates and explains current subjects such as cumulative, concerted and cooperative feedback inhibition and metal ion activation. ... Read more

Reviews (2)

Enzyme Kinetics Bible
This technical treasure is the bible of enzyme kinetics. Any enzyme mechanic or kineticist who has somehow missed this little tome does not know what they are missing. My copy is in tatters from freqent use and will have to be replaced soon...

An honored place on my bookshelf.
Segel's book is the ultimate in enzyme kinetics. I bought my first copy in 1978 and have probably used it 300 times since then. It deserves an honored place on every biochemists bookself. ... Read more

Book Description

Rodney Boyer's text gives students a modern view of biochemistry. He utilizes a contemporary approach organized around the theme of nucleic acids as central molecules of biochemistry, with other biomolecules and biological processes treated as direct or indirect products of the nucleic acids.

The topical coverage usually provided in current biochemistry courses is all present - only the sense of focus and balance of coverage has been modified. The result is a text of exceptional relevance for students in allied-health fields, agricultural studies, and related disciplines. ... Read more

Reviews (7)

A Cleverly Designed Book
Some biochemistry books proceed to describe metabolic pathways with scant reference to the physiological context in which they occur and then fill the conceptual gap by including a chapter on regulation and integration of metabolism. Not this thoughtful and cleverly designed book. From the start the authors make it clear that they are going to tell us the story in terms of one crucial unifying concept: which pathways are activated or inactivated when we eat or when we fast?

With this approach the reader never loses sight of the big picture, ie, what's going on in the body at any particular time. And then, when we do reach the chapter on integration of metabolism, most of the work has already been done for us: the chapter then operates as a useful review of what we have already been told.

The book does not miss any opportunity to make us think in terms of the big picture, and furthermore, it is never afraid of saying something more than once if it needs to. Just one example to illustrate this point: Lipoprotein lipase. Action and properties of this enzyme are detailed in the context of digestion of chylomicrons (p 497), storage of TAGs in adipocytes (p 512), integration of metabolism (p 561) and the influence of insulin levels on gene expression of the enzyme (p 564).

The early introduction of the fed and starved states is also useful in other ways. The student perceives right away what the point is of learning those endless metabolic pathways and studies them with much more enthusiasm and not just thinking that biochemistry is but an unnecessary obstacle they have to overcome to get to the more clinical stuff (at least I'd like to think so!). Inspired by this book I have organized my course in that way and I am convinced that it is the best approach.

Simple, Lucid, yet encylopedic
This book is different from its contemporaries in many ways. First of all is written in a clinical approach format which is very interesting for medical students. Most of the biochemistry textbooks are dry and vast and difficult to grasp the information needed for a medico.
But the Marks helps to learn to use biochemistry in the process of Clinical Problem Solving. With a lot of diagrams and clear text it is easy understand.
The Clinical Material is presented in the form of real patients.
It is a student friendly text with which you can learn biochemistry in a funny way of solving the clinical cases.
It can be used as a main textbook for self study.
I strongly recommend the Marks for all medical students.

Marks Biochemistry
This books is great.If you want to leran biochemistry within a month,buy it.I think it is the best book.It is perfect for your exam.

Not Pretty Good for USMLE
Texts are not easily to follow. Diagrams and help notes scatters around pages which make readers confused. If you are preparing for Step 1, I recommend you study Lippincott Biochemistry, Board Review Series.

This is the best biochemistry book (easy and comprehensive)
I love this book on biochemistry simply because it was the easiest to read, with diagrams and pictures even dumb people like me can read (gg). I also found that it is very comprehensive also. Some of the other titles I've read on the subject (Lippincott, Harper's) did not go into the detail of this one. Another positive note is that this is a clinical book also; giving you case studies in each chapter to test your knowledge. I can't say enough about this book and even referred it to one of my friends. Although not required in Chiropractic College (Lippincott was), it should have been the standard. ... Read more

Book Description

Patch clamping is a widely applied electrophysiological technique for the study of ion channels; membrane proteins that regulate the flow of ions across cellular membranes and therefore influence the physiology of all cells.

Patch Clamping aims to cover the basic principles and practical applications of this important technique. Starting with a review of the history of patch clamping, the text then goes on to cover the basic principles, platforms, equipment and environmental control, and will also include coverage of preparation types, recording modes and analysis of results.

• This book will explain the basic principles and practical application of patch clamp electrophysiology.
• Written in a non-technical style to ensure its broad appeal to novice users
• Takes a practical approach
• This self-contained guide provides everything a practising patch clamp electrophysiologist needs to know to master this technique, including an overview of membrane biophysics, standard experimental design, data analysis, and technical concerns

Reviews (1)

The first of its kind
I'm giving this book a high rating because it fills a niche for which no other text exists: An absolute beginner's guide to patch-clamping. Yes, you could read Neher & Sakmann's hefty "Single Channel Recording" but, for the complete novice patch-clamper, it's a bit overwhelming.

So, you walk into a patch-clamp lab, there's a million different things on the rig and you're feeling very confused. The microscope is much more complex than the microscope you remember from high school, there's cabling literally everywhere, and everybody keeps mentioning how important it is not to disturb the "voodoo" shielding.

Where do you start? What do all those instruments do? Will I ever patch a cell on my own? This is the book for you.

The book does an excellent job explaining the main components on a patch-clamp rig (and advice for setting up your own if you're just starting up a lab) and gives detailed instructions on whole-cell patch clamp techniques. (I have not evaluated the single-channel techniques but they too seem quite well written.) Also, many simple "equivalent circuit" diagrams are given so that you can understand what you're measuring. You will patch successfully after reading this book!

My only criticism is that the book is a bit skimpy on what to do after you've got the cell patched. Only a few voltage-clamp techniques are explored and there is very little on experiments using dual recordings.

Otherwise, it's an excellent book. If you're new to patch-clamping, this is (literally) the only book for you. ... Read more

Book Description

Over the years Bettelheim,Brown, and March's INTRODUCTION TO GENERAL, ORGANIC AND BIOCHEMISTRY has become the most respected and best-selling General, Organic and Biochemistry (GOB) textbook on the market. Known for the successful way it meets the needs of students who take this course--from re-entry students to those heading directly into careers in the allied health fields--the book is acclaimed for the way it provides students a solid chemistry foundation that will serve them well long after they leave the course. In this edition, the authors continue the hallmarks that have made their book a classic in the field: a pedagogically rich learning framework; a wide variety of medical and biological applications; a visually dynamic art program, innovative "Chemical Connections" essays that focus on current issues in general organic, and biochemistry; and exceptionally strong and varied end-of-chapter problems. At the same time, they have extended their student focus by providing a greatly expanded interactive CD-ROM, as well as a new "Career Corner" portion on the Book Companion Web site designed to help students make the connections between the chemistry they are learning today and their future careers. This edition gives students a solid foundation of the chemistry of the human body, consistently demonstrating that a strong background in molecular structure and properties leads to better understanding of biochemical interactions. The strength of this book is its readability, its application to normal human biochemical pathways, as well as discussing biochemical conditions present in diseases. The authors provide a unified view of chemistry, frequently using organic and biological substances to illustrate principles of general chemistry. ... Read more

Reviews (4)

Good for people with no knowledge of Biochemistry
I am currently trying to use this book for a Biochemistry course that I am taking. Considering that I have close to "Zero" knowledge in Chemistry, this is probably the best book that I can use for a variety of reasons (see below)

1) Book is in color

2) Although best to study the book chronologically, its not impossible to skip chapters. There is a great Glossary index at the back of the page which has some definitions written into them. Furtheremore definitions seems to be clearly/concisely written throughout the book, very helpful.

3) Examples written throughout the book with soultions.

4) Parargraphs are kept to a minimum so that you wont get too bored reading through the text.

I am giving this book a 4, but from my limited experience of looking at chemistry books this is the best one thats out there.

It won't be a breeze studing this book, but there are many more books out there which makes the task of studying chemistry a lot harder then it is.

Love this site..
I ordered this book, and it came faster than I expected it too. All and all the service was exceptional. You should purchase it here. I had already purchased this book from our campus bookstore to compare it. It was the same, and the book was in excellent condition. So were all the other textbook that I purchased on here. They came just as described, if not better. And all my books came within 3 days. I will purchase from here again.

Makes Complicated Ideas Easy
I checked this book out at my local college and kept renewing it so I could finish more chapters. Finally I ran out of renewing times and decided I really needed to own my own copy.

The book is detailed and precise. It is relatively hard yet light on math and what there is is explained well. It has great graphics and clear explanations that make the most advanced topics easy to visualize and understand. The problems at the end of the chapter are great for review.

It's the best introductory chem book I've ever seen. Better than any chem course.

Simple learning for an advanced class
This book is excellent for the Bioorganic chemistry. I went into my class terrified and overwhelmed. I was actually able to follow along better with the book than my actual teacher. The diagrams are clear cut and gives many examples. I love the factual clips in every chapter about nature or medicine and how this all relates to bioorganic chemistry. I found the clips a breather and a break from the complicated matter. This book finds a way to explain one thing in many different ways so that even the beginner can comprehend it at an advanced level. This book got me through the class with an A. ... Read more

Book Description

This handbook of valuable information extracted from laboratory manuals published by Cold Spring Harbor Laboratory Press is presented in an easy-to-use format.It contains invaluable reference data, never before assembled in one handy package.It has been assembled from extensively field-tested manuals, ensuring accuracy and reliability, by two scientists with extensive and diverse experience of laboratory practice. ... Read more

Book Description

The polymerase chain reaction (PCR) is now the standard method for amplifying nucleic acids and continues to find many new applications in basic, applied, and clinical research.Comprehensively updated and revised, this second edition of the best-selling "PCR" is designed as an introduction to the technique with authoritative coverage of a wide range of current applications. It includes current PCR applications such as genome mapping, pathogen detection, and quantitative PCR. The appendices include a comprehensive glossary of terms and listings of suppliers of instruments, reagents and consumables.From reviews of the first edition: "a very useful text and reference for new and experienced PCR users, I would rate it well above other recent texts that I have examined on the subject."

-- Trends in Cell Biology"This is a highly readable volume that could profitably be read by anyone about to employ PCR techniques, or who simply requires a basic understanding of the many manifestations of in vitro amplification." -- SGM Quarterly"the authors have succeeded in providing a viable introduction to PCR for researchers who are new to the technique, and also additional useful information for the veteran user. The balance between simple basic information and more specialized techniques is achieved making this a very useful book." -- TIBTECH ... Read more

Book Description

An Introduction to Molecular Medicine and Gene Therapy

Edited by Thomas F. Kresina, Ph.D. Gene therapy, or the use of genetic manipulation for disease treatment, is derived from advances in genetics, molecular biology, clinical medicine, and human genomics. Molecular medicine, the application of molecular biological techniques to disease treatment and diagnosis, is derived from the development of human organ transplantation, pharmacotherapy, and elucidation of the human genome. An Introduction to Molecular Medicine and Gene Therapy provides a basis for interpreting new clinical and basic research findings in the areas of cloning, gene transfer, and targeting; the applications of genetic medicine to clinical conditions; ethics and governmental regulations; and the burgeoning fields of genomics, biotechnology, and bioinformatics. By dividing the material into three sections - an introduction to basic science, a review of clinical applications, and a discussion of the evolving issues related to gene therapy and molecular medicine-this comprehensive manual describes the basic approaches to the broad range of actual and potential genetic-based therapies. In addition, An Introduction to Molecular Medicine and Gene Therapy:
* Covers new frontiers in gene therapy, animal models, vectors, gene targeting, and ethical/legal considerations
* Provides organ-based reviews of current studies in gene therapy for monogenetic, multifactoral or polygenic disorders, and infectious diseases
* Includes bold-faced terms, key concepts, summaries, and lists of helpful references by subject in each chapter
* Contains appendices on commercial implications and a review of the history of gene therapy

This textbook offers a clear, concise writing style, drawing upon the expertise of the authors, all renowned researchers in their respective specialties of molecular medicine. Researchers in genetics and molecular medicine will all find An Introduction to Molecular Medicine and Gene Therapy to be an essential guide to the rapidly evolving field of gene therapy and its applications in molecular medicine. ... Read more

Reviews (3)

Excellent overview of a fascinating field
I did not have any special prior knowledge in biology or genetics. I needed to quickly get up to speed in this area for a professional reason. Parts of the book were a little difficult to understand at times, especially when it used many technical terms, but overall it provided me with an excellent overview of this fascinating and rapidly evolving field. I reduced one star because of not seeing enough illustrations and diagrams which in my view are essential in any text that includes complex concepts. With this book I also read "Genomes" to complement the basics of Genomics and together these two books did the trick!! Strongly reccomended to anyone who is interested in the field.

.
The greatest difficulty with this field is that it is currently evolving at a rapid rate. Thus, books on the subject run the risk of being outdated before publication. However, Kresina and co-authors have done a solid job of reviewing existing methodologies, ethics and regulation of gene therapy as well as identifying some of the diseases for which this novel type of therapy could be applied. --Grant MacGregor, Emory University

An outstanding introduction
I am very impressed with the breadth of subjects that Dr. Kresina covered and how he was able to relate their associations with either molecular medicine and/or gene therapy. More importantly, he draws the two disciplines together in a logical and constructive manner. The book is not only an outstanding introduction to molecular medicine and gene therapy, but will be a valued reference guide for much of the information contained in the chapters. The topics are timely and most of the authors extremely well known and respected in their respective fields. While the second section of the book is primarily the clinical application, it draws very nicely from the more basic science introductory chapters. Chapters 13-15 and the Appendix provide a discussion of issues which undoubtedly will become significantly associated with advances in molecular medicine and gene therapy. The book is laid out in an easy-to-read format and provides ready access to a variety of different subjects. The index is inclusive and the chapters cover their individual areas in an up-to-date manner..."An Introduction..." should remain an outstanding introduction and reference text for a variety of students - from undergraduate to postdoctoral to all levels of faculty and investigators. --Clifford J. Steer, M.D., University of Minnesota Medical School ... Read more

Book Description

This volume covers the fields of origin, evolution and phylogenesis from prokaryotic to eukaryotic cells. The eminent authors, experts in their fields, review the three kingdoms of life (Archea, Eubacteria and Eukarya) from molecular evolutionary levels to ecological aspects in enigmatic habitats, including general reviews of puzzling pro--and eukaryotic organisms and their domains. We discuss dry habitats, thermophilic (cells in hot springs and undersea thermal vents up to 110`C), psychrophilic (cryophiles) and halophilic (high salt concentrations) niches which among the harshest conditions found on Earth where microbial life is frequently detected. Some chapters deal with the organisms which grow in extreme pH conditions (acidity vs. alkalinity), and under hydrostatic pressure in the deep sea, and microbial growth on petroleum. Other contributors present their research on aerobiology and microbes growing in various gases and various levels of radiation, including cellular morphological modification in these extremophilic microbes. This volume also includes the symbiotic association between two or more organisms on the endocellular and exocellular levels. Finally one paper identifies the extremophiles as candidates for exobiology. This is a valuable comprehensive volume in English that covers most of the extremophiles in a new light with current research data.Audience: Students, lecturers and researchers; scholars in the fields of biology, evolutionary biology and chemistry, and other evolutionary fields, and the intelligent layman. ... Read more

Book Description

Principles and Reactions of Protein Techniques describes the principles and reactions for most techniques of protein extraction, purification, and characterization. The author focuses on the principles and mechanisms of the experimental procedures and describes the reactions involved. He includes useful advice on which techniques to use and when to apply a particular method. The book discusses the advantages and disadvantages of various protein techniques, enabling students and researchers to master the mechanisms behind the protocols. Seven chapters cover most protein techniques in a consistent format that makes the material easy to retrieve. ... Read more

Book Description

Biochemical Pathways An Atlas of Biochemistry and Molecular Biology Edited by Gerhard Michal Modern biochemistry is a complex field, combining areas of cell biology, molecular biology, medicine, immunology, genetics-even neuroscience. Many of these disciplines converge in the dynamic arena of research dealing with metabolic processes and other mechanisms present at the cellular and molecular level. Biochemical Pathways offers a truly unique road map to modern biochemistry. In full and vivid color, it features detailed charts-each color-coded and accompanied by a brief explanation-of metabolic pathways and their relationship to regulation pathways. Important mechanisms of molecular biology are reviewed in the second part of the book. This encyclopedic compendium goes well beyond traditional biochemistry to cover some very specialized pathways and many aspects of regulation. The clear, systematic presentation includes:
* Metabolic structures and reaction mechanisms
* The intermediates and enzymes involved
* Metabolic branching points
* Transcription and translation
* Signal transduction
* Transport mechanisms
* Blood coagulation, immunology, and the complement system
Current, referenced, and easy-to-use, Biochemical Pathways is bound to become a classic in the field. It is a one-of-a-kind visual guide for researchers and scholars in all areas of the life sciences. ... Read more

Reviews (3)

Excellent. A MUST for anyone in biochemistry and endocrine
This is by far the best written and illustrated book for pathways I have ever seen. If I was teaching a course, it would be absolutely required.

"Bichemical Pathways"...Great content, Poor Presentation
Comprehensive references of bochemical pathways are not common, especially with well described cofactors, modulators, and interactions with disparate pathways. This book could provide such a useful reference, unfortunately, the quality of the layout is so poor as to make it very difficult to read. Poor graphic quality, exceptionally small fonts, and poor color choices render what should be a most useful reference into a visually challenging document. At the price, the book is a disappointment, although the content is great. One wishes that the editors would rerelease it after completely revising the graphics and production quality, as the content is indeed very useful.

"Biochemical Pathways..." - An excellent reference guide
The book "Biochemical Pathways..." is the book of choice if you quickly need information on a particular biochemical reaction, substrate or enzyme and serves well as an excellent reference guide. It is a comprehensive book version of the well-known Boehringer Mannheim wallchart "Biochemical Pathways" that can surely be found in almost every laboratory on the world. The book is color-coded and in addition to the enormous biochemical wallchart data gives a large body of overview information about fundamental aspects concerning enzyme structure, viruses and even the immune system. ... Read more

Reviews (1)

Bridging the gap from physics to cell biology
I wish there was a way to give a book more than five stars, because if there was, this book would get them! One of the most important trends in cell biology in recent years is the study of mechanics at a single molecule level. Since most of the really interesting processes in cell biology, such as division and motility, ultimately are carried out by molecules that convert energy into motion, the question of how these molecules actually move has very broad implications and impinged on everyone. However, in order to understand this, one has to understand some basic physics which of course involves some math. The biologist who is interested in this subject thus has two, and only two options. one is to bury one's head in the sand and say its just too hard to understand, and the other is to read Joe Howard's book. Although the mathematical content is readily apparent, only the basics are needed to get started. The author has thoughtfully compiled detailed derivations at the end in an appendix, so that one can see the details without becoming enmired in them on first reading. Considering the potential difficulties of taking a "hard science" approach to cell biology, the book is remarkably easy to read, which is a tribute to the thought the author has put into presenting the subject in the most logical possible way.
In addition to being an excellent entry point for biologists into this subject, this book would also be an excellent resource for engineers who become interested in cell biology (like myself) because it presents many of the current research frontiers in cell biology from an essentially engineering perspective and using quantitative reasoning. Again, the author has taken great pains to present the subject in a logical way that does not require much prior knowledge about biology on the part of the reader. Thus, either for biologists who want to learn about the quantitative/physical approach to cell biology, and for engineers or physicists who want to learn how they can apply their type of thinking to problems of cell biology, this book is highly recommended. ... Read more

Book Description

Enzymes--living substances that regulate health--work with certain minerals in our bodies to form an antioxidant system that fights corrosive free radicals. This fully updated second edition explains how to make the most of this amazing natural partnership to speed recovery from injury and lessen the effects of back pain, multiple sclerosis, viruses, and fatigue.

Reviews (2)

Enzymes-Enzyme Therapy by Dr. Cichoke MD
This book explains the mechanics of enzymes within the food
processing apparati of the body. These enzymes occur in all
living things. There are approximately 3000 enzymes which exist to ward off disease, assist the heartbeat, repair tissues, digest
food and perform a variety of important functions in the body.
The author explains how proteases breakdown protein.
i.e. histidine, leucine and tryptophan

There is a pH balance which consists of acids and alkalines
in a net balancing interaction within the body. Digestion
happens in the small intestine. There are extensive secretion
processes in the body i.e.
o saliva 1000 ml.
o gastric juices 1500 ml.
o pancreas 1000 ml.
o bile 1000 ml.
o small intestine 1800 ml.
o large intestine 200 ml.

Digestive processes are disturbed with improper tooth
alignment, diminished acid secretion, pancreatic insufficiency,
celial disease, lactose intolerance, stress. Digestion can
be helped by some of the recommendations contained in this book.
Various enzyme products can facilitate the digestive processes.
Soy sauce is a well-known enzyme enhancer. In addition, raw
veggies will assist in the process of enzyme interaction.
The author reviews an overall strategy to maximize enzyme
activity within the body consisting of:
o veggies
o garlic and onion
o minimum use of aluminum
o reduced salt intake
o reduced sugar
o an increase in bulk
o no coffee and smaller meals
o pineapple and papaya
o enzyme co-energizers Co-Q 10 ( coenzyme), zinc, red meat, nuts,
B vitamins., magnesium (Mg.), iron (Fe), copper (Cu.) and
Selenium (Se)

Overall, this work has a wealth of information pertaining to
personal health maintenance. It should be in every medical/
nutritional library.

Enzymes and Enzyme Therapy...
Dr. Cichoke shows how every life process depends on enzymes. He covers a broad range of subjects starting with digestion, elimination, co-enzymes, how to obtain more enzymes in your diet and through supplementation. He has a 5-step program of do's and don'ts, including avoidance of aluminum cookware, refined sugars and salt, coffee, and so on. He also tells you how and what to eat and how to prepare foods for the best utilization of enzymes. Dr. Cichoke addresses a large range of health problems from extending life to AIDS and cancer. He also covers medications that affect enzymes, including OTC drugs and prescription drugs, as well as foods that contain enzyme inhibitors. This is a great book! One I believe everyone should own. I also would strongly suggest Dr. Cichoke's book "The Complete Book of Enzyme Therapy". This book is set up very much like the "Prescription for Natural Healing", however it addresses health from an enzyme point of view. I would rate them both a 5-star, must have if you care at all about your health. This book was required reading for my Enzymes class, "The Complete Book of Enzyme Therapy" was not, but after reading this one, I wanted to know more. This book is a great intro to enzymes, the complete book goes even further. It is in fairly simple to understand language if you have a bit of medcial background, you might need a medical dictionary if not. ... Read more