Book Description

Genomics is a new discipline that is revolutionizing the way biological and medical research is done. The human genome is almost completely sequenced, which will help to accelerate research and development in Genomics even more. The chapters in this book try to capture the rapidly evolving field. Overviews of nucleic acid technologies, proteomics and bioinformatics are followed by chapters on applications, including human health, agriculture and comparative genomics. The book also includes two chapters on legal and ethical issues of Genomics, a topic that is becoming more and more important. ... Read more

Book Description

Bioinformatics brings computational methods to the analysis and processing of genomic data. Bioinformatics: Databases and Systems focuses on the issues of system building and data curation that dominate the day-to-day concerns of bioinformatics practitioners. Included are chapters by many of today's leading bioinformatics practitioners, describing most of the current paradigms of system building and curation, including both their strengths and weaknesses. Biological topics covered include sequence databases, metabolic pathways, phenotypes, variety collections, gene expression atlases and neuroinformatics. Species range from bacteria to mammals to plants. Software systems and technologies covered include OPM, CORBA, SRS, KLEISLI, ACEDB, Web-based integration and laboratory workflow.Bioinformatics: Databases and Systems provides a valuable introduction for newcomers to the field, and a useful reference for veterans. ... Read more

Book Description

Bioinformatics, in this context the application of computer science to biological problems, has become an indispensable part of any research in the biosciences. Rapid developments in gene sequencing, structure determination as well as rational protein engineering and design have made it necessary for biologists, chemists, and computer scientists to channel their expertise into large scale collaborative projects.
This GBF Monograph gives a general overview of the latest versatile activities in bioinformatics:
* Biological Data Bases
* DNA and RNA
* Protein Sequences and Structures
* From Molecules to Cell Metabolism

The articles have been selected from contributions to a conference on Bioinformatics/Computer Application in the Biosciences, held in October 1995 in Braunschweig at the German National Research Center for Biotechnology. ... Read more

Reviews (2)

Good to see whats around, Bad for developers
Not a bad book for Bioinformatics users who want to see what is around but this kind of information dates very rapidly.

Not a very good book for people interested in developing for bioinformatics (although it may prevent you from reinventing the wheel)

An overview of the software tools for Molecular biology
This book gives an overview of the powerful suite of software tools available for various computer applications of molecular biology. The initial chapters talk about many programs(comparisons, Database searching, sequence analysis, Gene Finding, pattern recognition, etc.) and web-based interfaces in addition to the utilities for sequences, databases etc., packed in Wisconsin package apart from short briefs of how to use these tools in a desktop environment. Also this book gives the details of sequence analysis tool called Omiga and its diverse functionalities.

Biological Sequence analysis software like MacVector and Lasergene gets enough attention in this book. Also sequence type-dependent and platform-independen tools like PepTool and GeneTool are also explained in detail.

Two important applications in molecular biology, gene identification and biological pattern detection have received a greater significance here. There is also a chapter about network computing for biologists.

This book lists out a set of free molecular biology software available in different web servers. A lot of relevant information about the journals online, research institutions and organisations and biological information repositories with their web site details and references are also accommodated. There are separate chapters for web-based resources for NCBI(National Center for Biotechnology Information)and EBI(European Bioinformatics Institute) besides a number of computing resources for geneticists.

In contrast to the notion of using mathematical and computational methods for solving different problems in modern biology, there is a chapter on computing with DNA, which talks about using chemical properties of DNA sequences to design a universally programmable molecular computer.

The editors have taken greater efforts in covering almost all vital tools and packages like Staden package, FASTA3 package, CLUSTAL programs, Primer3 on the WWW and Genotator in addition to phylogenetic Analysis using PHYLIP and low cost gel analysis.

On the other hand, the editors could have asked for a couple of more chapters on designing CORBA servers towards true interoperability of diverse biological databases, wrapping of legacy applications , integrating various biological software tools and desiging user-friendly graphical user interfaces using the new entrants like Java and CORBA.

Still this is a very good book for those with a thought of plunging into this ever-growing field of Bioinformatics. ... Read more

Book Description

This book constitutes the refereed proceedings of the Second International Workshop on Biologically Motivated Computer Vision, BMCV 2002, held in Tübingen, Germany, in November 2002. The 22 revised full papers and 37 revised short papers presented together with 6 invited papers were carefully reviewed and selected from 97 submissions. The papers are organized in topical sections on neurons and features, motion, mid-level vision, recognition - from scenes to neurons, attention, robotics, and cognitive vision. ... Read more

Book Description

The Bioinformatics market in the Asia/Pacific (excluding Japan) is still considered to be in its nascent phase. With various countries launching significant strategies into life sciences, Bioinformatics has become a hot topic with countries, such as Singapore, Australia, Hong Kong, and Taiwan having set up Bioinformatics centers or institutes to offer the services required for extended genomics and bimolecular related research. More agencies from national health institutes in Thailand to pharmaceutical companies have also expressed plans for deploying the use of Bioinformatics usage in this market is expected to accelerate over the next five years in Asia/Pacific.

"The Bioinformatics Software market in Asia/Pacific (excluding Japan) is still very much in its infancy. As a result of the nascent nature of the market and the high usage of freeware and discounted software available under educational institute schemes," said Daphne Chung, senior analyst, Life Sciences and Healthcare, IDC Asia/Pacific. This market in 2002 is estimated to have been worth only US$14.4 million. However, IDC expects the market to grow at a CAGR of 50% over the forecast period.

Book Description

This second edition of a bestseller, Statistical Genomics and Bioinformatics, Second Edition presents unique and complete coverage of broad topics in statistical genomics. It features several new sections and chapters discussing areas such as sequence-based analysis, biochip data analysis, and generalized bioinformatics. The author also provides updated lists of statistical and linkage analysis software and their Web links, as well as SAS codes to help with difficult problems. Other chapters are revised or consolidated to present updated information. Statistical Genomics and Bioinformatics continues to serve molecular biologists, geneticists, biostatisticians, students, and computer programmers. ... Read more

Book Description

Bioinformatics is a discipline originated by the need of introducing order into massive datasets produced by new technologies of molecular biology: large-scale DNA sequencing, measurements of RNA concentrations in multiple gene expression arrays and new profiling techniques in proteomics.

The volume under preparation presents mathematical models in bioinformatics along with descriptions of inspiring biological problems and computer science tools necessary to cope with data. The material covered includes widely used applications in genomics and proteomics and later-generation techniques, which attempts at linking genetic information with structure and function of molecules, metabolic processes and whole cells.

Book Description

The revised lectures presented in this volume are based on a course given by leading scholars at the C.I.M.E. Summer School held in Martina Franca, Italy, in July 2000.The 11 revised chapters presented were carefully revised and cross-reviewed in order to provide competent coverage of mathematical methods for protein structure analysis and design. The topics addressed pinpoint major issues arising in the development and analysis of models, algorithms, and software tools devoted to the structure of proteins, all of which play crucial roles in structural genomics and proteomics. ... Read more

Book Description

The astounding diversity of the immune system and the complexity of its regulatory pathways makes immunology a combinatorial science. Computational analysis has therefore become an essential element of immunology research and this has led to the creation of the emerging field of immunoinformatics. This book is the first to feature thorough coverage of this new field.

Immunoinformatics facilitates the understanding of immune function by modelling the interactions among immunological components. Biological research provides ever deeper insights into the complexity of living organisms while computer science provides an effective means to store and analyse large volumes of complex data. Combining the two fields increases the efficiency of biological research and offers the potential for major advances in the study of biological systems.

This book encompasses key developments in immunoinformatics, including immunological databases, sequence analysis, structure modelling, mathematical modelling of the immune system, simulation of laboratory experiments, statistical support for immunological experimentation and immunogenomics.

The difficulties in effective application of bioinformatic tools in immunology arise at both ends of the spectrum: most immunologists have only a limited comprehension of sophisticated data analysis and applicability and limitations, while the average computer scientist lacks knowledge of the depth and complexity of biological data. The purpose of this book, therefore, is to present contributions from a multidisciplinary team of biologists and computer scientists to explore the issues related to better understanding of immune function and, in particular, to help apply new computer science methods to immunological research.

Related Novartis Foundation symposia:

247 In Silico Simulation of Biological Processes

Chair: Denis Noble

252 Generation and effector functions of regulatory lymphocytes

Chair: Jean-François Bach
... Read more

Book Description

This book constitutes the refereed proceedings of the 6th International Conference on Parallel Problem Solving from Nature, PPSN VI, held in Paris, France in September 2000.The 87 revised full papers presented together with two invited papers were carefully reviewed and selected from 168 submissions. The presentations are organized in topical sections on analysis and theory of evolutionary algorithms, genetic programming, scheduling, representations and operators, co-evolution, constraint handling techniques, noisy and non-stationary environments, combinatorial optimization, applications, machine learning and classifier systems, new algorithms and metaphors, and multiobjective optimization. ... Read more

Book Description

Bioinformatics - the use of computers to retrieve, process, analyze and simulate biological information - promises to revolutionize the process of drug discovery and development. This book provides a broad, application-oriented overview of this technology. Contributions by internationally renowned specialists in the field afford a detailed insight into single bioinformatics components and algorithmic methods. In addition, the state-of-the-art in bioinformatics is evaluated equally from a global view by introducing real application scenarios such as genome projects that require the use ofa whole set of bioinformatics tools.

The profound knowledge on bioinformatics presented here not only enables readers to go beyond a mere push-button approach to using bioinformatics software and interpreting the data generated appropriately. It is also essential to assess the potential and limitations of today's bioinformatics software and future challenges. Directed to all those involved in the use or development of new bioinformatics tools - scientists and managers from the fields of molecular biotechnology, pharmaceutics, and medicinal chemistry - this book will lead one step further on the way to rational drug design ... Read more

Book Description

Molecular bioinformatics comprises the development and application of algorithms for the purpose of analysis, interpretation and the design of experiments in the biosciences. The heterogeneous collection of original research presented in this book illustrates the use of the wide and diverse range of algorithmic techniques. The application of algorithms from computer sciences, including artificial intelligence, machine learning, genetic programming, evolutionary algorithms and neural nets to molecular biology especially DNA and RNA sequence analysis and protein engineering is broadly examined. Both algorithmic and biological background problems are explained for an interdisciplinary audience. Readers: bioscientists, computer scientists. ... Read more

Book Description

This book constitutes the refereed proceedings of the 9th International Conference on Extending Database Technology, EDBT 2004, held in Heraklion, Crete, Greece, in March 2004. The 42 revised full papers presented together with 2 industrial application papers, 15 software demos, and 3 invited contributions were carefully reviewed and selected from 294 submissions. The papers are organized in topical sections on distributed, mobile and peer-to-peer database systems; data mining and knowledge discovery; trustworthy database systems; innovative query processing techniques for XML data; data and information on the web; query processing techniques for spatial databases; foundations of query processing; advanced query processing and optimization; query processing techniques for data and schemas; multimedia and quality-aware systems; indexing techniques; and imprecise sequence pattern queries. ... Read more

Book Description

This digital document is an article from Life Science Today, published by DMG World Media Ltd. on April 1, 2002. The length of the article is 631 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Hitachi's `Hitagene'--a major advance in pinpointing disease; in the hunt for genetic disease, Hitachi's bioinformatics system could make analysis 100 times quicker. (Ireland).(Brief Article)
Publication: Life Science Today (Magazine/Journal)
Date: April 1, 2002
Publisher: DMG World Media Ltd.
Volume: 3Issue: 2Page: 8(1)

Article Type: Brief Article

Distributed by Thomson Gale ... Read more