Book Description

This book constitutes the refereed proceedings of the 9th Annual International Computing and Combinatorics Conference, COCOON 2003, held in Big Sky, MT, USA in July 2003. The 52 revised full papers presented together with 3 invited contributions were carefully reviewed and selected from 114 submissions. The papers are organized in topical sections on computational geometry, computational biology, computability and complexity theory, graph theory and graph algorithms, automata and Petri net theory, distributed computing, Web-based computing, scheduling, graph drawing, and fixed-parameter complexity theory. ... Read more

Book Description

Completely revised and updated, this new edition of a bestseller will continue to serve as a tool that allows researchers to easily access and use databases to gather information on genes, proteins, and diseases. It covers new approaches to data analysis using databases around the world. It identifies computing techniques that help readers manage the massive flow of information. The structure of this second edition will follow that of the first and its content will reflect the growth in information. New sections cover recent developments in genome projects, microarray, proteonics, brain mapping, and more. ... Read more

Reviews (5)

I liked it but it could use more sample problems
I wanted to learn something about informatics...The book was easy to understand but it lacked practice problems... This is not a religious book...Obviously the book takes an evolutionary stand point since the entire concept of bioinformatics is based mainly on evolutionary similarities of proteins and other cellular components. If you are new to bioinformatics but have some understanding of Biology, then you should get this book...

An expensive hodgepodge
Books about bioinformatics are as diverse as the field itself. It may not be possible to do justice to this new and exciting field in 168 pages. My concern with this book, however, lies not with the choice of topics, but rather with its incoherent presentation. Distracting parenthetical remarks pervade the text as in this excerpt from the beginning of the 3rd chapter: "DNA sequences are often found based on predictive tools, meaning that sequence similarities of newly discovered genes yield information about their physiological functions and structures, PCR (polymerase chain reaction), finding sequence fragments of significance (how is significance judged? By predictive biology, once again), finding distribution of genes or mRNAs (often an indicator of gene activity in an organism), and amplifying the amount of DNA for purification, sequencing, and mutational analysis." (p. 143).

Chapter 5 entitled "The Computer Revolution in Neurobiology" we find the following unexpected text: "One rationale for human cloning is that it could alleviate many of the problems associated with our unique characteristics. The genetic information (DNA) of a cloned organ is identical to that of the individual needing the organ. Hence, the cloned organ would be accepted by the individual's body as part of itself and would have a smaller probability of rejection." (p. 159). [Nevermind the enormous ethical implications!]

Throughout, one has the sense of a book rushed to market to take advantage of an exciting scientific trend. The book presents nothing that can't be found on-line and it gives readers no sense of the computational challenges of the field. ...

I own this title in my library and is well worth the money!
I am a novice in bioinformatics and have found this book to be invaluable in getting me started without intimidating me. I have owned the book for over a year and still find it very useful but I am waiting for an update to this title soon since I have enjoyed the organization of the book. It has given me a global picture of informatics and chapters with specific examples and applications. I am sure a second edition to this book will be well recieved by the audience and I am hoping to see it soon since the new bioinformatics book I have just purchased is not to my liking.

Solid starting place for a novice
I'm always looking for a good guide book for undergrads and biocomputing novices that covers the basics without getting carried away with algorithmic minutiae. I found this book a fair place to start for those who have no idea of what is out there. The tools and Web sites described are mainstays and likely won't be going anywhere. However, if you are already moderately knowledgeable, you will exhaust this book immediately. The nature of the field is constant movement toward newer and more thorough tools. This is not a users' guide: go to the referenced Web sites themselves to get the most up to date, accurate information.

I would refer a naive beginner to get this book at the library, but I wouldn't put it on my own shelf.

Bioinformatics to the max!
This is truly a great book. I had always wondered about biological research and the use of computers. The future of medicine and mankind will be changed drastically by new advances created by the coupling of science and technology. Bioinformatics is the wave of the future and Rashidi shows in his book that he is far ahead of his time. He has written the kind of book, a "gold standard" if you will, upon which all other texts in the field shall be judged. If I were taking a class which covered the subject of bioinformatics, I would definitely want this to be my resource for information. Clear, concise and unpretentious, Rashidi lays everything out vividly so that anyone from the undergraduate to the post-graduate student may marvel at the wonders of bioinformatics. My only complaint is that I think it should have been titled "The Bible of Bioinformatics" because its wealth of information is so epic and complete. There is no need to look for another book. Rashidi's has it all! ... Read more

Book Description

The LNCS journal Transactions on Rough Sets is devoted to the entire spectrum of rough sets related issues, from logical and mathematical foundations, through all aspects of rough set theory and its applications, such as data mining, knowledge discovery, and intelligent information processing, to relations between rough sets and other approaches to uncertainty, vagueness, and incompleteness, such as fuzzy sets and theory of evidence.This third volume of the Transactions on Rough Sets presents 11 revised papers that have been through a careful peer reviewing process by the journal's Editorial Board. The research monograph "Time Complexity of Decision Trees" by Mikhail Ju. Moshkov is presented in the section on dissertation and monographs. Among the regular papers the one by Zdzislaw Pawlak entitled "Flow Graphs and Data Mining" deserves a special mention. ... Read more

Book Description

The LNCS journal Transactions on Computational Systems Biology is devoted to inter- and multidisciplinary research in the fields of computer science and life sciences and supports a paradigmatic shift in the techniques from computer and information science to cope with the new challenges arising from the systems oriented point of view of biological phenomena.

This first volume of the Transactions on Computational Systems Biology is made up of papers by members of the journal's Editorial Board to provide a representative and smart start-up to the new journal.

Book Description

Over recent decades vast amounts of biological data have been accumulated. However, it is becoming increasingly difficult to apply traditional theoretical methods to the formulation of coherent pictures of cell and organ function because it is no longer possible for a human theorist to integrate all of the available information. Instead, computer technologies must now be used to perform this integration. This book brings together contributions from many different fields to summarize the current status of computer-assisted modelling of biological processes.

The initial chapters deal with fundamental developments in hardware, software and mathematics that underlie current approaches to biological modelling. Next, different approaches to collating data on gene structure and function are presented. These databases form a vital resource for any investigator trying to construct an integrated picture of particular biological systems.

Cell signalling systems form a particularly complicated aspect of all cellular function and are important both in the understanding of basic cellular processes and in selecting targets for drugs. Recent approaches to integrating data on cell signalling into computer models are covered. Further chapters build on these approaches to show how computerized models of intact cells can be developed. Finally, approaches to the computer modelling of whole organs such as the heart are presented. The role of computer modelling in drug design is the subject of the final chapter and is also touched on throughout the discussions.
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Reviews (1)

Better simulations
In 1988, at Los Alamos, I was in a research group that did simulations of hair cells in the inner ear. These were then state of the art, and involved modelling the transport of various elements like potassium across the cell boundaries.

But computer hardware has improved enormously since then. Along with the understanding at the cellular level of many processes. So now, "in silico" simulations have become feasible for a wide range of biological systems. This book explores that range. From single cells to clusters/networks of cells, all the way up to entire organs.

At all these levels, different assumptions have to be made to render practical computational results. You can judge for yourself whether the assumptions are justified, and perhaps how future advances in hardware will let us relax these. ... Read more

Book Description

This book constitutes the refereed proceedings of the Third International Conference on Evolvable Systems: From Biology to Hardware, ICES 2000, held in Edinburgh, Scotland, UK, in April 2000.The 27 revised full papers presented were carefully reviewed and selected for inclusion in the proceedings. Among the topics covered are evaluation of digital systems, evolution of analog systems, embryonic electronics, bio-inspired systems, artificial neural networks, adaptive robotics, adaptive hardware platforms, molecular computing, reconfigurable systems, immune systems, and self-repair. ... Read more

Reviews (1)

A good review of new topics
This is a fine medium-advanced book on evolvable hardware.The book contains some of the very latest material you will be able to find available on print or in the internet.Specially, I find very interesting the immunotronics approach from the University of York staff. ... Read more

Book Description

This digital document is an article from Worldwide Databases, published by Worldwide Videotex on September 1, 2000. The length of the article is 383 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: ERAGEN/TIMELOGIC FORM BIOINFORMATICS COLLABORATION.
Publication: Worldwide Databases (Newsletter)
Date: September 1, 2000
Publisher: Worldwide Videotex
Volume: 12Issue: 9Page: NA

Distributed by Thompson Gale ... Read more

Book Description

This digital document is an article from Health Law Review, published by Health Law Institute on March 22, 2004. The length of the article is 7381 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Gene meets machine: intellectual property issues in bioinformatics.
Author: Suneeta D'Souza
Publication: Health Law Review (Magazine/Journal)
Date: March 22, 2004
Publisher: Health Law Institute
Volume: 12Issue: 2Page: 34(10)

Distributed by Thomson Gale ... Read more

Book Description

This book constitutes the refereed proceedings of the Third International Symposium on Medical Data Analysis, ISMDA 2002, held in Rome, Italy, in October 2002. The 23 revised full papers presented were carefully reviewed and selected for inclusion in the book. The papers are organized in topical sections on data mining and decision support systems, medical informatics and modeling, time series analysis, and medical imaging. ... Read more

Book Description

This book constitutes the refereed proceedings of the 13th Annual International Symposium on Algorithms and Computation, ISAAC 2002, held in Vancouver, BC, Canada in November 2002. The 54 revised full papers presented together with 3 invited contributions were carefully reviewed and selected from close to 160 submissions. The papers cover all relevant topics in algorithmics and computation, in particular computational geometry, algorithms and data structures, approximation algorithms, randomized algorithms, graph drawing and graph algorithms, combinatorial optimization, computational biology, computational finance, cryptography, and parallel and distributedd algorithms. ... Read more

Book Description

This book constitutes the refereed proceedings of the Third International Workshop on Algorithms in Bioinformatics, WABI 2003, held in Budapest, Hungary, in September 2003. The 36 revised full papers presented were carefully reviewed and selected from 78 submissions. The papers are organized in topical sections on comparative genomics, database searching, gene finding and expression, genome mapping, pattern and motif discovery, phylogenetic analysis, polymorphism, protein structure, sequence alignment, and string algorithms. ... Read more