Book Description

This volume and its companion, Volume 338, supplement Volumes 176, 177, 239, and 261. Chapters are written with a "hands-on" perspective. That is, practical applications with critical evaluations of methodologies and experimental considerations needed to design, execute, and interpret NMR experiments pertinent to biological molecules. ... Read more

Book Description

Soft Condensed Matter commonly deals with materials that are mechanically soft and, more importantly, particularly prone to thermal fluctuation effects. Charged soft matter systems are especially interesting: they can be manufactured artificially as polyelectrolytes to serve as superabsorbers in dypers, as flocculation and retention agents, as thickeners and gelling agents, and as oil-recovery process aids. They are also abundant in living organisms, mostly performing important structural (e.g. membranes) and functional (e.g. DNA) tasks.

The book describes the many areas in soft matter and biophysics where electrostatic interactions play an important role. It offers in-depth coverage of recent theoretical approaches, advances in computer simulation, and novel experimental techniques.Readership: Advanced undergraduate level in physics, physical chemistry, and theoretical biochemistry. ... Read more

Book Description

Hardbound. This volume contains papers of 23 outstanding scientists who are working at the leading edge of metabolic regulation studies.Much of the volume focuses on novel aspects of signal transduction with emphasis on the role of phospholipase C in cell control mechanisms.

One of the highlights of this volume is always the Special Symposium Lecture.This lecture was given for fifteen years by Nobel laureate, Sir Hans A. Krebs (UK) (now deceased).This year the Lecture was given by Nadir Maraldi, Director of the Laboratory of Cellular Biology and Electron Microscopy, University of Bologna, Italy.Professor Maraldi's presentation is on the important and novel subject of "Nuclear Proteins and Human Disease." ... Read more

Book Description

This volume is based on a symposium in honor of Professor Ingvar Lindgren. It includes a contribution by Dr. William D. Phillips, who was awarded the 1997 Nobel Prize in the field of physics for work on the development of methods to cool and trap atoms with laser light.
Advances in Quantum Chemistry publishes surveys of current developments in the rapidly developing field of quantum chemistry--a field that falls between the historically established areas of mathematics, physics, chemistry, and biology. With invited reviews written by leading international researchers, each presenting new results, this quality serial provides a single vehicle for following progress in this interdisciplinary area. ... Read more

Book Description

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymologyis one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
This volume and its companions (Volumes 31 and 334) cover all current knowledge concerning hyperthermophilic enzymes. Major topics in this volume include enzyme discovery, saccharolytic enzymes, and proteolytic enzymes. ... Read more

Book Description

High Pressure Effects in Molecular Biophysics and Enzymology is designed to acquaint biochemists, biophysicists, and graduate students with advances in the application of high pressure in connection with spectroscopy as a research tool in the study of biomolecules.The 23 chapters written by leading authorities present an overview of current approaches to the use of high pressure in research on enzyme kinetics, protein folding and structure, lipid bilayer structure and organization, lipid-protein interaction, and DNA structure. This important, timely volume is the first devoted exclusively to high-pressure effects in biochemistry and will be the definitive reference in its subject for the next several years. ... Read more

Book Description

This book is intended to provide an in-depth understanding of 13C NMR as a tool in biological research. 13C NMR has provided unique information concerning complex biological systems, from proteins and nucleic acids to animals and humans. The subjects addressed include multidimensional heteronuclear techniques for structural studies of molecules in the liquid and solid states, the investigation of interactions in model membranes, the elucidation of metabolic pathwaysin vitro and in vivo on animals, and noninvasive metabolic studies performed on humans. The book is a unique mix of NMR methods and biological applications which makes it a convenient reference for those interested in research in this interdisciplinary area of physics, chemistry, biology, and medicine.

Key Features
* An interdisciplinary text with emphasis on both 13C NMR methodology and the relevant biological and biomedical issues
* State-of-the-art 13C NMR techniques are described; Whenever possible, their advantages over other approaches are emphasized
* The chapters constitute comprehensive reviews and are written by acknowledged experts in their fields
* Chapters are written in a clear style, and include a large number of illustrations and comprehensive references ... Read more

Book Description

Peter Mitchell, winner of the 1978 Nobel Prize for chemistry for his chemiosmotic theory, was a highly original scientist who revolutionized our understanding of cellular metabolism and bioenergetics.This is the only full biography of Mitchell, and it should be of considerable interest to biophysicists, biochemists, and physicians and researchers focusing on metabolism, as well as historians of medicine and biology. ... Read more

Reviews (1)

wanderings
I picked up this book because I had some familiarity with the subject matter having worked in that field of biochemistry in the late '60s. That is probably the main reason I read the whole thing and enjoyed it.
This is very much a scientific biography. It's an interesting story of the evolution a scientific idea (The Chemiosmotic Theory) and how that idea came to be accepted by the scientific community. The originator of the idea, the imaginative, ambitious, passionate Peter Mitchell, had to fight for many years to see his theory finally accepted.
I was disappointed, however, that the book did not paint a fuller picture of Mitchell who had many interests outside of science which are (frustratingly) alluded to - music, architecture, farming, family - but never explored. For example, the authors state that family life was very important to Mitchell but give no examples of how a highly motivated scientist/entrepreneur managed to fit it in. Nor is there any sense of what domestic life was like living in an isolated research institute/manor/farm. In my opinion, if these aspects of his life had been more developed, the book would appeal to a wider audience and the reader would come away with a fuller appreciation of the man.
Technically, it is rather a choppy book. Each chapter is divided into subchapters, which detracts from its cohesiveness. Repetition of some points also gives the sense that the book was pieced together.
However, I did read the whole thing and found it an interesting study of how 20th century science works - or works imperfectly. ... Read more

Book Description

This textbook presents the scientific basis for understanding the nature of food and the principles of experimental methodology as applied to food. It reviews recent research findings and specific technological advances related to food. Taking an experimental approach, exercises are included at the end of each chapter to provide the needed experience in planning experiments. Emphasizing the relationships between chemical and physical properties, basic formulas and procedures are included in the appendix.

Key Features
* Demonstrates the relationships among composition, structure, physical properties, and functional performance in foods
* Suggested exercises at the end of each chapter provide students with needed experience in designing experiments
* Extensive bibliographies of food science literature
* Appendix of basic formulas and procedures ... Read more

Book Description

As a new and exciting field of interdisciplinary macromolecular science and engineering, polymeric materials will have a profound presence in 21st century chemical, pharmaceutical, biomedical, manufacturing, infrastructure, electronic, optical and information technologies. The origin of this field derived from an area of polymer science and engineering encompassing plastic technologies. The field is rapidly expanding to incorporate new interdisciplinary research areas such as biomaterials, macromolecular biology, novel macromolecular structures, environmental macromolecular science and engineering, innovative and nano-fabrications of products, and is translating discoveries into technologies.

ú Unique in combining scientific concepts with technological aspects
ú Provides a comprehensive and broad coverage of thermodynamic and thermal behaviours of various polymeric materials as well as methodologies of thermal analysis and calorimetry
ú Contributions are from both pioneering scientists and the new generation of researchers ... Read more

Book Description

This beautifully written book is a study of the physical relationship between the inanimate environment and living organisms.It describes how the evolution of both has been interactive and interdependent; the authors show that this can be explained in terms of the properties of the chemical elements and their compounds. The book concludes with an examination of an intriguing problem: the long-term consequences of our manufacture and exploitation of chemicals. This intervention may be altering the symbiotic relationship between life and the environment, an issue of great concern to ecologists and biologists as well as those who study chemistry. ... Read more

Book Description

Accurate molecular structures are vital for rational drug design and for structure-based functional studies directed toward the development of effective therapeutic agents and drugs.Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding.

* Methodological methods in crystals
* Methodological methods data analysis ... Read more

Book Description

Broad in scope, this book describes the general theory and practice of using the Electron Capture Detector (ECD) to study reactions of thermal electrons with molecules. It reviews electron affinities and thermodynamic and kinetic parameters of atoms, small molecules, and large organic molecules obtained by using various methods.
* Summarizes other methods for studying reactions of thermal electrons with molecules
* Discusses applications in analytical chemistry, physical chemistry, and biochemistry
* Provides a data table of electron affinities ... Read more

Book Description

Lectures at the 1997 Les Houches workshop on 'Dynamical Network in Physics and Biology', held March 17-21, 1997. Demonstrates how biological systems use the properties of interconnected networks to regulate physiological processes. For researchers. Site of workshop is not cited. Softcover. ... Read more

Book Description

Protein Transcription is a key element of cellular and organ regulation.This volume covers structure and function of all major elements associated with transcription.

*Mechanism of RNA polymerase I Transcription
*Structure and function of RNA Polymerase II
*Structure and function of the TFIID complex
*Functional properties of Chromatin Remodeling Enzymes
*Posttranslational modification ... Read more