Book Description

The work of accident prevention in the lab begins with foresight. Discerning "close calls"—near accidents—early enough prevents them from turning into full-fledged mishaps, mishaps that cost time and money, and which could result in injury. Improving Safety in the Chemical Laboratory is an accident prevention handbook for the professional in the lab that shows how to detect and eliminate the causes of dangerous mishaps—and virtually "hazard proof" any lab environment. In unequivocally clear and practical terms, Improving Safety in the Chemical Laboratory, Second Edition offers detailed procedures—from precautionary labeling to simulated drills, safety inspections,and the preparation of a chemical hygiene plan—for the development of a safety-enhanced workplace. Reflecting, in part, the upgraded procedures now mandated by the OSHA Laboratory Standard in the USA, as well as the WHMIS regulations in Canada and the COSHH regulations in the United Kingdom, this newest edition offers unparalleled and up-to-date guidance on the fine points of hazard control, with new added material on managing and handling especially hazardous substances and personal protective equipment:

• The 95 percent solution: the list of causes of laboratory accidents
• Hazard categories: unsafe acts; unsafe conditions
• Selecting and maintaining personal protective conditions
• Accident handling
• Classes of fuels and fires
• Preventing and extinguishing fires
• Toxic effects of chemicals
• Recognition of and treatment for exposure
• Chemical specific safety protocol
• Storage of lab chemicals
• Safe disposal of hazardous waste
• Personal protective equipment in the laboratory
• Improving hood performance
• Designing safety into new or renovated laboratories

Reviews (2)

One of the best
This is definitively one of the best Clinical Chemistry books I know. At work I routinely need to consult information and this makes a great reference book to search for in depth explanations. Now, I don't feel this would be good for a student, I feel this book is a little dense and treats some issues in such a way that might be a little intricate for the first contact with them. I believe you need some practical work experience to really take all the juice out of it, though I don't mean I'm not recommending it to students. This is a great book to anyone, the only thing is I don't concieve it as a texbook (for this I'll better recommend Kaplan & Pesce "Clinical Chemistry", which is an easier reading while not compromising much depth).

it is great book
Tietz Fundamentals of Clinical Chemistry is great book spicailly for medical technology , u can find every detail , u need , i have the 3 rd , and the 4 th edition , and i will bring the 5 th ... Read more

Book Description

An accessible and quick introduction to the scientific study of drugs, including their composition, uses, and physiological effects. ... Read more

Reviews (1)

A must for the medicinal chemist
Reading this book is much easier after taking the author's course. You get a better feeling for how the book is laid out after listening to the author's lecture style. An organic chemist by training, the author naturally gears this book to the organic chemist. He gives just enough physiology to understand the pharmacology behind it. The book follows his lecture course fairly well with more in-depth discussion on topics of interest. A standard reference text that should be in any chemists' library starting out in the pharmaceutical field. ... Read more

Book Description

This definitive new book should appeal to everyone who produces, uses, or evaluates scientific data. Ensures accuracy and reliability. Dr. Taylor's book provides guidance for the development and implementation of a credible quality assurance program, plus it also provides chemists and clinical chemists, medical and chemical researchers, and all scientists and managers the ideal means to ensure accurate and reliable work. Chapters are presented in a logical progression, starting with the concept of quality assurance, principles of good measurement, principles of quality assurance, and evaluation of measurement quality. Each chapter has a degree of independence so that it may be consulted separately from the others. ... Read more

Reviews (1)

Quality Assurance of Chemical Measurements
This book is a valuable reference for quality managers and analysts in the laboratory. It covers many topics concerning quality assurance, and is easy to read and understand. It offers a good overview of the principals involved in a laboratory quality program. ... Read more

Book Description

This book is the fourth edition of a highly regarded text which was first published in 1988. It introduces the reader to the interpretation of routine laboratory biochemical test results and covers all aspects of interpretative chemical pathology (including reproductive endocrinology, which was not covered previously).

The approach is based on case material from the authors' laboratory and employs algorithms and similar aids for interpretation. The material is structured so that it is comprehensible to beginners as well as being useful for the more experienced practitioners. The envisaged audience is medical undergraduates, general practitioners, clinical biochemists and laboratory technicians. ... Read more

Book Description

From disease marker identification to accelerated drug development, this reference offers a detailed overview of current and emerging trends in the field of proteomics—focusing on innovations in protein microarrays and biochips, mass spectrometry, high-throughput protein expression, protein–protein interactions, structural proteomics, and the proteomic marketplace for comprehensive understanding of proteomic research in the past, present, and future. ... Read more

Book Description

The uses of computers in chemistry are many and varied, from the modelling of solid state systems to the design of complex molecules which can be used as drugs. This text provides an introduction to the many methods currently used by practising computational chemists and shows the value of computers in modern chemical research. The authors describe the various computational techniques available and explain how they can be applied to single molecules, to assemblies of molecules, and to molecules undergoing reaction. An introductory chapter outlines the hardware and software available, and looks at some applications and developments. Subsequent chapters cover quantum mechanics, molecular mechanics, statistical mechanics, the modelling of biomolecules, and drug design. While emphasizing the use of computers to model biological systems, the authors explain how the methods can be applied to a wide range of chemical problems. ... Read more

Reviews (2)

Conceptual, not practical foundation
What this book does, it does reasonably well. Its real strength is in the basic quantum mechanical principles that bind atoms and that cause molecualr interactions.

The authors carry this forward, using concise mathematics, to derive electron distributions and small-scale molecular conformations. The third chapter addresses conformations of larger molecules, starting with rigorous computations of each conformation's energy, then backing down to some approximation techniques. The fourth chapter packs in a number of concepts, prehaps too many: solvation, statistical mechanics, and a little bit of molecular mechanics. Chapter five skims over protein and DNA folding, and chapter 6 discusses small-molecule (drug) interactions with proteins.

Although the authors start the book noting the intense computational requirements, they never give explicit techniques for performing those computations efficiently. The math is the abstract form, close to the quantum mechanics, and rarely the form of a practical computation. In fact, the math is abstract enough that I'd be hard pressed to come up with real limits of integration in many cases. The authors make some effort to use their equations to support intuitive understanding, but sometimes focus too much on the formulas themselves instead of their meanings.

I can't fault the book for being written in 1995 - by the standards of computational chemistry, that's a bit dated now. Still, almost all of its references date from 1990 or earlier. They weren't the freshest even when the book was written.

The book does give a broad view, high-level survey of the quantum mechanical view of chemistry. It omits many more modern practices though: finite element approximations to molecule structure, grammar-based analysis of RNA folding, and Markov models for structure prediction. It also omits the knowledge needed to reduce abstract physics to practical calculations. Use this as an introductory survey, but use other books for knowledge you can put to work.

A concise introduction to Comp. Chem.
This small booklet is an excellent introduction to computational chemistry for the novice. Provides an easy to read, description of the field, its methods, applications and utilization. Covers everything: 'ab initio' quantum mechanics, molecular mechanics and dynamics, modelling of biological macromolecules with a short introduction to sequence analysis, QSAR and computational pharmacology.
While it won't provide an in-depth view of the methods, it manages to convey enough detail to understand the basics. A must have for anyone desiring to enter the exciting field of Molecular Modelling. ... Read more

Book Description

This is the first book to integrate the biological, nutritional, and health aspects of antioxidant status. Fifty contributors integrate and transfer the knowledge of free radicals and antioxidants from the test tube to the laboratory of the biologist, clinical nutritionist, and medical researcher, as well as to the office of the dietician, nutritionist, and physician. Topics examined include factors affecting and methods for evaluating antioxidant status in humans; effect of diet and physiological stage (infancy, aging, exercise, alcoholism, HIV infection, etc.) on antioxidant status; and the role of antioxidant status in nutrition, health, and disease. ... Read more

Reviews (2)

Excellent and comprehensive review of antioxidant research
The book is an excellent reference for anyone interested in the role of antioxidants in both food and biological systems. The contributors are leaders in their respective fields of research with many years of experience and outstanding credentials. I found the book to be a most valuable resource for personal enlightnment and for guidance in my quest for new and improved nutritional supplements for the industry.

Science and clinical knowledge about antioxidant supplements
This book is an example of a multidimensional book. It succeeded well in integrating topics of wide and current interest dealing with antioxidant status, nutrition, health and disease. The result is a book that is very readable and can benefit a broad spectrum of audiences. In addition to nutritionists, dietitians and health professionals, specialists from other disciplines such as chemistry, biochemistry, medicinal chemistry, pharmacy, and pharmaceutical sciences can benefit from this book.

Of particular interest is the extensive discussion of the role of diet and nutritional supplements in health and disease. These topics have attracted wide public interest and have been making national headlines in recent years. World class experts from academia, government and industry discuss these topics applying the same rules of scientific and clinical evidence used in the discovery and evaluation of new drugs. The high caliber of this discussion is representative of the overall quality of this book. ... Read more

Book Description

Pocket ALL the chemical process answers you'll ever need!

This "take-it-anywhere" Handbook gives you fast answers to virtually every conceivable question about chemicals, processes, safety, regulations, and industrial practices. It features up-to-date information on regulations and safety, including correct methods for handling chemicals and compressed gasses; best practice methods for the lab and on-line in the plant; information on process operations, both batch and continuous, with details on process analyzers, microprocessors, and computer applications; physical properties and determinations, plus help with pressure, vacuum, and plumbing issues; review of chemical calculations; energy, work, and power problems; mathematical formulas and applications; conversion tables; statistical quality control and charting methods, plus guidance on log books and batch records; first aid procedures and emergency treatment.

This rich source of reference material includes a glossary of process industry terms, important sourcebooks and governmental contacts. ... Read more

Reviews (2)

Essential Portable Reference for Chemical Plant Operators
There are a number of handbooks for scientists and engineers.The author's goal with this readily useable reference is to present those topics most useful to CHEMICAL PLANT AND EQUIPMENT OPERATORS. TheNST/Engineers, Inc. reviewers agree that the author has succeeded indelivery of those topics, and in a writing style and with graphicspresentations that will appeal to operators.Having worked with plantoperators for number of years, we have found that they can work in thisfield for quite awhile and still have nagging questions about theproperties and reactions of chemical materials and physical measurementsinvolved in their daily work.This book leads them to many answers. Supervisors of operators should consider placing copies of this handbook inthe hands of their operators.The supervisors themselves, plant engineers,and most plant personnel will find the book to be a handy deskreference.

The book begins by covering industrial safety topics.MajorOSHA regulations affecting operators are listed.For the sake of brevityand to maintain true "pocket-guide" size, regulations are cited anddescribed however, since the full text is available on the internet, theirinclusion would just be clutter.Safety in handling of chemicals getsspecial attention.For self-protection, operators need every safetyreminder they can practically use.

The U.S. Chemical Safety and HazardInvestigation Board reports that, on average, there are roughly 60,000"commercial - chemical" incidents per year. At plant sitesthere have been about 30 deaths per year and about 1,000injuries.

Chemical plant operators are regularly called upon to makephysical property determinations.They and must clearly understand the"short-hand" of chemical nomenclature.The author covers the most commonproperties (melting point, boiling point, flash point, density, specificgravity, viscosity, and surface tension) together with sketches ofequipment arrangements for their measurement.

It is necessary for thechemical operator to understand not only what the job entails but the moreimportant issue to the operator may be understanding why certain thingsoccur. Some basic knowledge of inorganic and organic chemistry isnecessary to provide these answers. In several sections, the authorprovides a unique blend of rudimentary, basic explanations of matter, howto read the periodic table of the elements, chemical bonding, chemical andstructural formulas, figuring molecular weights and chemical naming.Ofevery day use is the discussion of molecular, mass, and volumerelationships along with a detailed discussion of solution terminology andacids and bases.The chemical families are clearly described along withtheir occurrence and uses in industry and specific precautions to take whenhandling them.

All employees who deal with chemicals in the workplaceare required by OSHA to be trained in the Hazard Communication Standard orHAZCOM.In the section of the handbook on Chemical Handling, chemicallabeling and packaging are well covered.Also covered are:materialhandling (forktrucks), bonding and grounding (flammable materials), spillcleanup for the different groups of chemicals, and chemical disposal. Confined spaces (such as tanks, vats, columns, reactors, and mixers), thatare usually encountered in the chemical process industries, are defined andOSHA's Permit Entry system is explained.Lock-Out / Tag-Out and Blanking,both of which are integral parts of the confined space standard, aredefined and illustrated.Having several years of OSHA training experience,it is one reviewer's opinion that this section, along with the section onMSDSs, if mastered, would fulfill OSHA's requirements for HAZCOMtraining.

As the primary means of conveying liquid and gaseous chemicalsis by pumps and compressors, understanding the section on pressure andvacuum is essential.Thorough coverage is given to the operation andtroubleshooting of pump systems along with explanations of pressure andvacuum measurement.These explanations will help prevent the confusionmany operators experience with psig and psia measurements, for instance. The reader will also learn how different types of pressure gaugeswork.

Other sections such as Fluid Mechanics and Plumbing, StandardOperating Procedures, Basic Electricity, and Process Operations containinformation with which the chemical operator should already be familiar. However, they are excellent references none the less.The section onEnergy, Work and Power will take the guess-work out of chemical energy andelectrical power calculations, and pump and motor selection.

Throughoutthe handbook, the author provides tables, conversions, calculations, andexamples that allow readers to "test" their mastery of the informationpresented in a given section.

The NST/Engineers, Inc. reviewers believethat this handbook should be provided by supervisors to their employees asan aid to answering those frequent questions such as when I do this, whydoes that happen? Also, why do we do it this way?

This is the best instructional manual ever written!
This has a lot of very helpful information that can be used immediately ... Read more

Book Description

Most medicinal chemists working in the pharmaceutical industry are organic synthetic chemists with little or no background in medicinal chemistry.These chemists must acquire a good knowledge of medicinal chemistry during their firstyears in the pharmaceutical/drug discovery industry. This bookaims to be their practical handbook - a complete guide to the drug discovery process.

The book reviews practical aspects of Medicinal Chemistry, emphasising the daily problems met by the medicinal chemist when dealing with lead discovery/identification methodologies, with structure-activity relationship studies aimed to scale up potency and target selectivity, and when optimising pharmacokinetic and pharmaceutical properties by means of ultimate chemical modifications.

This is the second edition of The Practice of Medicinal Chemistry, the first edition being published in February 1996.The new edition is thoroughly revised, with around 30% new material, and refocussed to reflect the recent developments in genomics, proteomics, high throughput screening of compounds and drug solubilisation.An effort has been made to remove the overlap that exists in the previous edition and four new chapters have been introduced.

* Written by experts in the field
* The first edition of The Practice of Medicinal Chemistry, published in 1996, was nicknamed 'The Bible' by medicinal chemists.
* The only available book dealing with the practical aspects of medicinal chemistry, from conception of the molecules through to the production of drugs
* An essential practical handbook for the medicinal chemist, working in the pharmaceutical industry, withlittle or no background in medicinal chemistry-a complete guide to the drug discovery process. ... Read more

Reviews (1)

Pls help me to get this book.
I want to buy this book. I am in Japan. Would you pls tell me how I can get this book. ... Read more

Book Description

Gas Mixtures provides practical suggestions and calculations for producing multicomponent test gas atmospheres. General topics addressed include sorbent evaluation, methods development, dosimeter testing, instrument calibration, atmospheric simulation, and gas analysis. Learn the tricks of the trade for producing gas mixtures over a wide range of concentrations using even the most difficult-to-handle materials. Gas Mixtures is a must for industrial hygienists, air pollution control specialists, analytical chemists, and others working in such areas as health and safety, air pollution, air cleaning, and respirator and carbon research. ... Read more

Reviews (5)

I'm no pathologist and I love it.
I'm a chemist and in my practical experience in the laboratory I have to say this is probably the best text you will find if you are a analytical reader. Of course, this book is not written with a enjoyable style, but if you bear to read it carefully and really analize the details, you will not regret the effort. This is great for reference and if it wasn't so dull in style It will make a great job as a textbook too, besides this is a classic.

Very useful for pathology residents
I rate this book a "4" as it is essential reading for residents in pathology. A large number of the pathology board questions come directly from this book, making it necessary reading. It's also VERY dry reading, even for a pathology textbook. However, due to its importance in studying for the boards, I highly recommend it.

Extremely Useful
I'm medical student from Hong Kong. I find it very useful in preparing Problem-based-learning tutorilas. The interpretation of the laboratory results are the most useful. It helps me understand more in the PBL cases.

A must for every doctor
Simple and delightful , filled with nice illustrations this book is necessary to every doctor not only clinical pathologists and laboratorits but everyone who handles daily with ambulatory and infirmary pacients. A must in every uptodate doctor or even meddicine students bookshelf.

Supurb text
This reference receives from all reviewers the top recommendations for comprehensive, concise, understandable presentations. Every laboratorian needs this reference. The 20th edition is due in February, 2001. ... Read more

Book Description

Destruction of Hazardous Chemicals in the Laboratory George Lunn and Eric B. Sansone This comprehensive guide contains a series of procedures for the safe destruction of a wide variety of hazardous chemicals and also describes how to deal with spills. Each procedure is presented in great detail, thereby eliminating the need for additional references, and most have been extensively validated by international collaborative studies. In addition, many procedures have been tested to see if the final reaction mixtures are mutagenic. 1990 (0 471-51063-7) 271 pp. Chemical Protective Clothing Performance Index Book Krister Forsberg and Lawrence H. Keith This valuable reference contains data on breakthrough times and permeation rates for 650 chemicals and mixtures. The tests performed on over 200 chemical protective clothing (CPC) models—gloves, suits, boots, visors, etc.—were developed by the American Society for Testing and Materials (ASTM). The book also discusses the various types of materials used in protective clothing and considers variations in CPC performance due to differences in materials, chemical additives, and manufacturer. 1989 (0 471-51430-6) 308 pp. Ventilation for Control of the Work Environment William A. Burgess, Michael J. Ellenbecker, and Robert Treitman A sourcebook for the specification, design, installation and maintenance of industrial ventilation systems, this text brings the concepts and principles of ventilation into an industrial setting while establishing a theoretical background as well. Emphasizing practical aspects, this book covers principles of fluid mechanics, methods and instrumentation for measuring air flow, hood design, selection and performance, and the design of local exhaust ventilation systems. Air cleaning devices, replacement air systems, and the technology and equipment for conditioning the air in the workplace are also discussed. 1989 (0 471-89219-X) 476 pp. ... Read more

Book Description

This unique reference provides a pragmatic approach to the development of successful commercial immunodiagnostic products based on enzyme immunoessay technology. Presenting both the basic and applied principles, Enzyme Immunoassays gathers information on all aspects of this process, from the initial conceptualization to the introduction of the product to the market. ... Read more

Book Description

Minimizes the amount of chemicals used in the lab and resultant chemical waste. Introduces new experiments designed to reduce exposure to toxic materials, lab costs and environmental pollution. Covers basic chemical concepts as well as spectroscopy and solution, physical and inorganic chemistry. Also presents several viable macroscale versions of experiments. Includes a glossary of terms as well as appendices of scientific tables and information. ... Read more