Book Description

This volume describes the important application of the Bio- or DNA-Chips in biomedical research such as gene expression studies and methods of construction. Details novel optical sensing and processing technologies that are being employed by researchers in this field. Specific topics include DNA Chips, detection technologies, and optical sensing and processing. ... Read more

Book Description

There has been much interest in the introduction of nucleic acid-based analysis techniques into diagnostic laboratories and routine screening procedures. This timely book, written by practicing exponents, presents an up-to-date introduction to the molecular diagnosis of human disease, including genetic diseases, cancer and viral bacterial and parasitic infections. It focuses on the technology, theory and approaches of molecular methods to diagnose human disease, including genetic diseases, cancer, and infections.

This book is suitable for students, practitioners and researchers in medical genetics and molecular medicine. ... Read more

Book Description

Pioneered by the pharmaceutical industry and adapted for the purposes of materials science and engineering, the combinatorial method is now widely considered a watershed in the accelerated discovery, development, and optimization of new materials.Combinatorial Materials Synthesis reveals the gears behind combinatorial materials chemistry and thin-film technology, putting forth the prime techniques involved in synthesis and property determination for experimentation with a variety of materials. ... Read more

Book Description

Examines fluorescence spectrometry with special emphasis on its applications to biochemistry. Fluorescence techniques are particularly useful because of their very high sensitivity and selectivity, especially when used in connection with chemical techniques for forming fluorescent derivatives. HPLC techniques are incorporated throughout and the utility of fluorescence when coupled with HPLC is explored. ... Read more

Book Description

Covers preliminary test and chromatographic methods in forensic drug testing. Reviews identification methods such as molecular spectrophotometry, nuclear magnetic resonance, and mass spectrometry. Discusses the fundamental relationship between instrumentation and drug analysis. Evaluates the characteristics and pretreatment approaches for common sample categories. Presents in-depth test result interpretation on issues commonly encountered in workplace drug urinalysis. Analyzes and compares performance characteristics of immunoassays commonly used for workplace drug urinalysis. ... Read more

Book Description

The new edition of this extremely successful text explores the clinical application of biochemistry. It explains what happens to the body's chemistry when affected by disease¡Kwhich laboratory tests are used in various clinical situations¡Kand how to interpret the results. Over 100 actual patient case histories demonstrate how clinical chemistry relates to the practice of medicine. More than 100 crisp line drawings¡Xrendered in full color for the first time in this 5th Edition¡Xmake concepts easy to understand. And, self-assessment exercises based on clinical vignettes enable readers to check their comprehension of the material.

„h Presents more than 100 real patient case histories that demonstrate the clinical applications of the content.
„h Delivers over 100 crisp line drawings¡Xnow rendered in full color¡Xto clarify important principles.

Includes a variety of self-assessment exercises to test readers' comprehension. ... Read more

Book Description

This book provides an introduction to basic concepts in the design of safe laboratories.Many of the chapters in this volume are based on papers presented in a symposium sponsored by the American Chemical Society's Committee on Chemical Safety and the Division of Chemical Health and Safety. Topics covered within the book include different perspectives on the design of safe laboratories, generic issues affecting the design of safe laboratories, ventilation and fume hoods, putting laboratory design and safety principles into practice, and working together to design safe laboratories. This publication is intended for individuals and businesses interested in incorporating safety design into laboratory construction and remodeling projects. ... Read more

Book Description

This book details advances in the studies of chemical dynamics and photochemistry using emerging laser technologies. It examines both theoretical and experimental advances in this field and includes such topics as efficient selectivity in chemical reactions, new pulse shaping techniques, and new tool for realistic control and manipulation of molecules. ... Read more

Reviews (1)

This book stinks
The Lab book is the amost ambiguous piece of material ever written to mankind. I dont suggest any Chemistry student to use this book if he wants to still enjoy the subject. With this book I've grown a strong disliking for Chemistry Lab. The book provides no clear instructions for the procedures and therefore makes lab confusing and frustrating. A WASTE OF MONEY ... Read more

Book Description

Hardbound. Highlights of this volume include comprehensive accounts of the biological rationale, design and clinical potential of new drug molecules; valuable summaries of structure-activity relationships in topical areas of medicinal chemistry; and expert evaluation of new technologies in their application to drug action and design.The seven chapters of this volume describe exciting advances in new drug molecules and in the application of new technologies to drug discovery and development.

Chapter 1 provides a comprehensive account of p38 mitogen-activated protein kinase inhibitors, a new class of anti-inflammatory agents with potential application to rheumatoid arthritis, inflammatory bowel disease and psoriasis, as well as other disorders with an inflammatory component.

A timely review on ligands for adenosine A3 receptors in Chapter 2 focuses on potent and selective agonists and partial agonists derived from adenosine, but demons ... Read more

Book Description

Laboratory facilities are complex, technically sophisticated, and mechanically intensive structures that are expensive to build and to maintain.Hundreds of decisions must be made before and during new construction or renovation that will determine how successfully the facility will function when completed and how successfully it can be maintained once put into service.

This book provides guidance on effective approaches for building laboratory facilities in the chemical and biochemical sciences.It contains both basic and laboratory-specific information addressed to the user community-the scientists and administrators who contract with design and construction experts. The book will also be important to the design and construction communities-the architects, laboratory designers, and engineers who will design the facility and the construction personnel who will build it-to help them communicate with the scientific community for whom they build laboratory facilities. ... Read more

Reviews (1)

A bureaucratic approach to laboratory design
As always, the title of a book does not tell us its true content and scope. In this case the title and the content match, but in a very bureaucratic way. The ideas are carefully worded, but all the design challenge and the exemplification through images are gone. There is not a single image or exemplification diagram inside the book. It is an excellent INTRODUCTION to the design activities and concepts for a general-but-somewhat-specialized architectural task, but it is simply bothersome to professionals with a harsh need of an updated guidance in the technological and normative issues involved in that kind of interdisciplinary work. Had the book included the word "Introduction" my personal sense of deception was not so assured and asserted. If you want an introduction to that field before more deep technical literature, this book is really worth of each dollar you pay for it. ... Read more

Book Description

Intended specifically for practicing professionals and advanced students in chemistry and biochemistry, this invaluable book covers the full range of the computer applications in these fields, including numerical, nonnumerical, and graphics applications. New material includes multiple linear regression using MREG, principal-components analysis, Monte Carlo integration, parameterization of the force field, and molecular modeling software.

Major areas covered include:
* Error, Statistics, and the Floating-Point Number System
* Curve Fitting
* Multiple Linear Regression Analysis
* Numerical Integration
* Numerical Solution of Differential Equations
* Matrix Methods and Linear Equation Systems
* Random Numbers and Monte Carlo Simulation
* Simplex Optimization
* Chemical Structure Information Handling
* Mathematical Graph Theory
* Substructure Searching
* Molecular Mechanics and Molecular Dynamics
* Pattern Recognition
* Artificial Intelligence and Expert Systems
* Spectroscopic Library Searching and Structure Elucidation
* Graphical Display of Data and of Molecules

Whatever your area of research, this comprehensive, lucidly written book offers an indispensable resource of computer applications that will facilitate your work. ... Read more

Book Description

The origin and early years of any rapidly changing scientific discipline runs the risk of being forgotten unless a record of its past is preserved. In this, the first book-length history of clinical chemistry, those involved or interested in the field will read about who and what went before them and how the profession came to its present state of clinical importance. The narrative reconstructs the origins of clinical chemistry in the seventeenth century and traces its often obscure path of development in the shadow of organic chemistry, physiology and biochemistry until it assumes its own identity at the beginning of the twentieth century. The chronological development of the story reveals the varied roots from which modern clinical chemistry arose. ... Read more

Book Description

The Compendium is a detailed compilation of chiral auxiliaries which are used in the field of organic chemistry to direct "asymmetric synthesis".A molecule is called chiral because it can have two "enantiomers" -- like left and right-handed molecules.An enantiomer is either of two molecules of the same chemical composition that are mirror images of each other but not identical.A "chiral auxiliary" is an aid / auxiliary used to specifically produce either the left or right enantiomer of the chosen molecule, as desired.In this comprehesive reference source, industrial chemists can make informed selections of an auxiliary for a specific application. It is fully cross-referenced to enable the comparative selection of auxiliaries. The work includes over 13,000 auxiliary reaction applications with complete reaction details of the synthetic routes, reagents, and primary literature references.

Key Features
* This remarkable major reference work is the first such compilation and represents the only total source for the diverse applications of auxiliaries
* Thoroughly cross-referenced to enable comparative selection of auxiliaries to be made dependent on target application
* Includes more than 13,000 auxiliary reaction applications with complete reaction details for each auxiliary
* Includes over 2,700 references, for reactions involving all recyclable chiral auxiliaries, published through mid-2000
* The material is compiled in a manner that facilitates its use as a reference source for practitioners of asymmetric organic synthesis in making an informed selection of an auxiliary for a specific application ... Read more

Book Description

Successful Management of the Analytical Laboratory provides a comprehensive discussion of the problems that face analytical laboratory managers and presents proven techniques for improving the operation and performance of analytical labs. A wide range of topics are covered, including functions of various laboratory types (including a discussion of legal proceedings that involve defending laboratory data), staffing and organization, motivation, management and development of personnel, personal relations and communication, sample handling, workload optimization, equipment selection and justification, budgeting and cost control (including methods for calculating the dollar return on investments in capital equipment), and information management systems.The book emphasizes measures that managers can take to ensure quality performance in both the laboratory and its personnel while maintaining the overall cost effectiveness of the operation.The author uses case histories from his experience to illustrate the application of the management principles presented in this excellent book for new and experienced lab managers alike. ... Read more