Book Description

Internationally acclaimed for more than forty years, this serial, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of the rapidly expanding field of the chemotaxonomy, structureelucidation, synthesis, biosynthesis, and biology of all classes of alkaloids from higher and lower plants, marine organisms, or various terrestrial animals. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. Over the years, this series has become the standard in natural product chemistry to which all other book series aspire. The Alkaloids: Chemistry and Pharmacology endures as an essential reference for all natural product chemists and biologists who have an interest in alkaloids, their diversity, and their unique biological profile.

Key Features
* Indispensible reference work written by leading experts in the field
* Provides up-to-date, timely reviews on compounds and classes of great interest
* Covers synthesis, biosynthesis, biology, as well as isolation and structure elucidation
* An essential research tool for anyone working with alkaloids from a chemical or biological perspective ... Read more

Reviews (1)

potential therapeutic alkaloids
Alkaloids have diverse biological activities and offer a rich source for development of new therapeutic agents. ... Read more

Book Description

From the days of the alchemists through the creation of the modern laboratory, chemistry has been defined by its instruments and experimental techniques. Historians, however, have tended to focus on the course of chemical theory rather than on the tools and experiments that drove the theory. This volume moves chemical instruments and experiments into the foreground of historical concern, in line with the emphasis on practice that characterizes current work on other fields of science and engineering. The principal themes are: change and stability, precision, the construction and transformation of apparatus, the dissemination of instruments, and the bridging of disciplines through instruments.

The essays are divided into three chronological sections: The Practice of Alchemy (reviewing the material and iconographic evidence as well as the written record and the issue of reproducibility of alchemical experiments), From Hales to the Chemical Revolution (discussing significant seventeenth- and eighteenth-century innovations as well as smaller innovations that cumulatively extended the reach and improved the quality of chemical experimentation), and The Nineteenth and Early Twentieth Centuries (discussing the increasingly important role of innovative apparatus as chemistry grew into the first large-scale modern scientific discipline).

Contributors: R. G. W. Anderson, Bernadette Bensaude-Vincent, Maurice Crosland, Jan Golinski, Frederic L. Holmes, Trevor H. Levere, Seymour H. Mauskopf, William R. Newman, Mary Jo Nye, Lawrence M. Principe, Alan J. Rocke, Colin A. Russell, William A. Smeaton, Melvyn Usselman. ... Read more

Book Description

A thoroughly revised and expanded edition of a best-selling classic reference on principles and practice of medicinal chemistry and drug discovery. Volume 1 covered principles. Volumes 2 through 5 focus on drugs that target a particular organ or system. ... Read more

Reviews (1)

the ultimate book
I have seen many books on medicinal chemistry, but this book is an outstanding publication. It covers all chemistry, pharmacology, history and approach to new drug design. It gives complete information required for ascientist.

This is the best book for medicinal chemistry. ... Read more

Book Description

All the information you need to create a high-performance, cost-effective, fully automated laboratory facility

Understanding how to apply the tools of data handling has become as much a part of the scientist's skills as doing a clinical study, unraveling a gene sequence in DNA, or conducting an experiment in high-energy physics. Yet too often laboratory automation is implemented on a costly, one-project-at-a-time basis. This unique guide surveys the current generation of laboratory computing equipment and procedures, explores the diverse computing needs and opportunities in the modern laboratory, and gives scientists, technicians, managers, and information systems personnel the strategic perspective they need to take full advantage of rapidly developing technology. Laboratory and Scientific Computing provides complete information on state-of-the-art computing environments and emerging technologies such as neural networks, artificial intelligence, and hyper-information systems.

The methods described in this book enable scientists and managers to evaluate each technology both in terms of its immediate impact on specific projects and its broader effect on the information handling of the laboratory as a whole.

This broad-based approach facilitates:

• Cost reduction through the elimination of faulty design
• Improved use of data and information
• Improvements in validation programs thereby reducing system validation costs
• Low-cost integration of emerging technologies
• Improved ability to meet regulatory requirements

Book Description

Combinatorial chemistry in conjunction with High Throughput Screening (HTS) is revolutionizing the drug discovery process.

The chapters in this book represent the state of the art regarding the integration of combinatorial chemistry and HTS in connection with anti-inflammatory targets. This text should set the stage for creative thinking among scientists of many disciplines for the accomplishment of our ultimate goals in treating inflammatory diseases. ... Read more

Book Description

The present book is an outstanding summary of many aspects of cannabinoid research. It provides current knowledge about the pharmacology and therapeutic potential of cannabinoids as well as knowledge about the pharmacology, physiology, and pathology of the endogenous cannabinoid systems. The chapters are written by scientists who have made or are still making major contributions to the field. This book may well help generate novel ideas on how to approach the study of emotions. ... Read more

Book Description

This volume reviews current data collection systems, examines unique approaches to data collection and storage, and provides the latest information on regulatory issues on data capture, storage, and reporting. ... Read more

Book Description

Vanadium is now known to be one of the more biologically important transition elements. This volume focuses on vanadium chemistry and biochemistry and summarizes the role of vanadium in treating diabetes, concluding with a discussion of a recent human trial study. ... Read more

Book Description

Immunochemistry is of immense importance to virtually all areas of modern biology and medicine; as a result, the wide range of related topics called for the space afforded by two volumes.This latest addition to the Practical Approach series provides a large body of valuable information in a clear and accessible format.The availability of high quality antibodies has been an essential prerequisite for progress in most areas of immunochemistry; the strategies used in their production are covered in Volume I.Other topics include the uses of antibodies in immunoassays, from the standardization of antigens and antibodies to the latest ELISA techniques; the application of enzyme immunoassays to cells; the latest refinements of photoluminescence immunoassays; and the incorporation of antibodies and their fragments into immunotoxins. ... Read more