Book Description

New exploration tools and techniques for a breakthrough paradigm of regional groundwater occurrence
Fresh water is undoubtedly our most precious resource aside from the air we breathe, and the only commodity whose cost has steadily risen over time. At the same time, our understanding of the origins, pathways, and recharge mechanisms of the earth's most valuable "economic" mineral-groundwater-remains in the nineteenth century. It is ironic that this scientific anachronism is contributing to a global shortage of available fresh water supplies while oil, gas, and mineral discoveries have proliferated, vastly increasing the world's energy, precious metals, and industrial mineral reserves.
Modern Groundwater Exploration details applications and results of proven twenty-first- century technologies and geological concepts adapted from the oil, gas, and mineral exploration industries for evaluating, developing, and managing previously undiscovered, massive, sustainable groundwater resources. Unprecedented in both its scope and authority, this timely book presents:
* A new groundwater paradigm, coined Megawatershed, which accurately and comprehensively describes the earth's natural complex groundwater systems
* Innovative exploration, drilling, and testing technologies that make major new ground-water sources more locatable and cost-effective to produce than ever before
* Actual case studies in which megawatershed methods have identified vast quantities of new water and brought new hope to previously arid and desperately water-short locales
* Chapters by former OECD DAC chairman Alexander R. Love, geopolitical analyst Dr. Ewan Anderson, and former director of the Trinidad and Tobago Water Resources Agency Dr. Utam Maharaj on the tremendous global implications of the megawater-shed paradigm. These experts explore the many beneficial applications of megawater-shed development, from macroeconomics to development of small island developing state (SIDS), and from critical environmental issues to water conflict resolution and the potential for a second "green revolution"
The world's need for clean, dependable water is more urgent-and addressable-than ever before. Let Modern Groundwater Exploration introduce you to the authors' revolutionary megawatershed paradigm, along with the latest concepts and technologies for accessing vast reservoirs of groundwater-still today's safest, cleanest, and most plentiful water resource. ... Read more

Book Description

Since their discovery earlier this century, phthalocyanines have been of great interest to chemists, physicists and industrial scientists.They remain one of the most studied functional molecular materials and a vast literature devoted to structure property relationships has evolved, based on the continuous advances in phthalocyanine synthesis.This book assimilates this information, using recent advances from the study of phthalocyanine-based materials to critically evaluate their potential role in emerging technologies.Following a brief historical overview and a chapter devoted to chemical synthesis, the book describes the various types of molecular and polymeric phthalocyanine materials. These include crystals, thin film fabrication including molecular epitaxial deposition and the Langmuir-Blodgett technique, composites, liquid crystals and self-assembled materials.The fundamental optical and electronic properties of these materials are explained and their potential in nonlinear optics, optical data storage, electronic sensors, xerography, solar energy conversion, nuclear chemistry, molecular magnetism, electrochromic displays and heterogeneous catalysis is evaluated. ... Read more

Book Description

This proven and well-tested laboratory manual for organic chemistry students contains procedures for both miniscale (also known as small scale) and microscale users. This lab manual gives students all the necessary background to enter the laboratory with the knowledge to perform the experiments with confidence. For the microscale labs, experiments were chosen to provide tangible quantities of material, which can then be analyzed. Chapters 1-2 introduce students to the equipment, record keeping, and safety of the laboratory. Chapters 3-6, and 8 are designed to introduce students to laboratory techniques needed to perform all experiments. In Chapters 7 and 9-20 students are required to use the techniques to synthesize compounds and analyze their properties. In Chapter 21, students are introduced to multi-step syntheses of organic compounds, a practice well known in chemical industry. In Chapter 24, students are asked to solve structures of unknown compounds. Chapter 25 introduces students to reading the literature in organic chemistry. ... Read more

Reviews (1)

A great help
This book writen by Gilbert and Martin provides an excellent help to the student who is currently studying organic chemistry. It is full of useful information and it provides assistance for the completion of the organiclabs. it is full of helpful pointers and they provide alot of usefulknowledge ... Read more

Book Description

A unique, integrated look at solid-phase synthesis and advances in combinatorial chemistry and technologies

The last decade has seen a rapid expansion in combinatorial technologies, a field where chemistry disciplines intersect with automation, statistics, and information science, as well as certain biological disciplines. Reflecting these multidisciplinary trends, this new work provides a comprehensive overview of the most important aspects of solid-phase synthesis (SPS), combinatorial chemistry, and related combinatorial technologies. It clearly demonstrates how SPS and combinatorial chemistry have extended their application from the pharmaceutical arena to new areas, including biotechnology, material sciences, catalysis, and agrochemical industries, and explores in detail strategies for planning, designing, preparing, and testing of combinatorial libraries in various disciplines. Designed to meet the needs of both experienced combinatorial chemists and newcomers to the field, Solid-Phase Synthesis and Combinatorial Technologies:
* Surveys the most recent developments in SPS and combinatorial chemistry
* Explains the entire process, from determining the need for a library to the details necessary for synthesis of the library
* Discusses choice of format, size, and the rationale behind the design of each synthetic step
* Surveys the analytical techniques and the purification methods used to characterize and purify combinatorial libraries
* Employs a large number of examples to illustrate important concepts
* Includes problems geared toward applying acquired knowledge and designing the steps to SPS/library synthesis
* Describes the quality control and activity screening of combinatorial libraries for various applications
* Features a detailed bibliography of more than 1,700 relevant sources ... Read more

Reviews (1)

A good book for beginner
This book gives a clear concept of solid-phase synthesis.
Good for beginner in this area. It also gives a lot of information including examples in some interesting application in the real synthesis. ... Read more

Book Description

Reflecting the increased pace of research and the many recent advances in organic chemistry, this series serves as a single-source compendium of the most up-to-date and significant procedures currently in use. ... Read more

Book Description

Over the years researchers have reported solubility data in the chemical, pharmaceutical, engineering, and environmental literature for several thousand organic compounds. Until now, this information has been scattered throughout the literature. Containing over 16,000 solubility data points for more than 4,000 organic compounds, Handbook of Aqueous Solubility Data provides an extensive compilation of published aqueous solubility data for a wide variety of organic nonelectrolytes and unionized weak electrolytes. It includes data for pharmaceuticals, pollutants, nutrients, herbicides, pesticides, agricultural, industrial, and energy related compounds. Each compound is identified by a sequential number along with molecular formula, compound name, synonyms, molecular weight, CAS Registry Number, melting point, and boiling point if available. Each entry has a five-point evaluation score for the quality of the reporting of the data, along with the full citation, and comments from the authors when necessary. The user-friendly format gives a clear depiction of each piece of solubility data with enough information to estimate its validity. Handbook of Aqueous Solubility Data gives you a portable, accessible resource for solubility data of numerous compounds and a single system for the evaluation of the data supplied. ... Read more

Book Description

This cutting-edge lab manual takes a multiscale approach, presenting both micro, semi-micro, and macroscale techniques. The manual is easy to navigate with all relevant techniques found as they are needed. Cutting-edge subjects such as HPLC, bioorganic chemistry, multistep synthesis, and more are presented in a clear and engaging fashion. ... Read more

Reviews (1)

Student of the Publisher: Winter quarter 2004
I think the book was excellent! And I would underline that word if I could. I am taking Daniel Palleros's Organic Chemistry right now. The only thing greater than his book is his teaching. I recommend it to any student or instructor teaching organic chemistry. ... Read more

Book Description

This text is aimed at a one-term course taken by allied health and agricultural science students.It includes annotated reaction summary tables, solved in-chapter examples, integrated applications (industrial, medical, etc.) and essays that describe organic chemistry's impact on the economy, environment, and the quality of life. ... Read more

Reviews (1)

Your Students Will Actually Read It!
This book condenses what is usually a gruelling two-semester curriculum into a brief but thorough text that can be navigated in a single semester. Concepts are summarized in easy to understand color tables. Each chapter contains an interesting aside/biography to keep students awake and show that the knowledge has important applications. The periodic table of elements and lists of primary organic functional groups are summarized inside the hard cover for quick reference. A solutions manual for the homework problems is sold separately. ... Read more

Book Description

This third of four volumes continues the work of its well-received predecessors by providing comprehensive articles on specific lines ofresearch. All volumes are written with medicinal chemists, organicchemists, physical chemists, and biological chemists in mind.Additionally, with the spate of recent research on the anticancer,antiviral, and antiparasitic properties of nucleosides andnucleotides, the volumes will interest oncologists, virologists, andpharmacologists. ... Read more

Book Description

A unique guide to variable temperature CD spectroscopy and its application in organic chemistry
This timely, original, thought-provoking work looks at organic stereochemistry from the perspective of circular dichroism (CD), using variable temperature CD spectroscopy to determine the conformation or absolute configuration of chiral molecules. With an emphasis on the analysis of optically active ketones and the carbonyl chromophore, the authors demonstrate the advantages of this highly sensitive spectroscopic tool for obtaining stereochemical information in diverse areas of organic chemistry, biochemistry, and medicinal/pharmaceutical chemistry. They combine detailed examples of stereochemical analysis with clear, thorough presentations, correlating chiroptical data with molecular mechanics calculations as well as data from NMR spectroscopy and other spectroscopic techniques. In addition, they provide a systematic survey of the professional literature, featuring an extraordinary collection of original CD spectra run at varying temperatures. Coverage includes:
* Chiroptical measurements: CD and ORD (Optical Rotatory Dispersion)
* Conformational analysis of compounds ranging from simple cyclic ketones to polycyclics
* Conjugated and homoconjugated systems
* Stereochemistry of the carbon-carbon double bond
* Stereochemistry from exciton coupling of two or more chromophores
* An interesting historical account of the development of stereochemical concepts ... Read more

Book Description

Jiro Tsuji, one of the pioneers in this field of organic synthesis, provides synthetic organic chemists with a remarkable overview of the many applications of organopalladium chemistry. Tsuji discusses the recent developments in the field as well as the explosive growth over the last five years.

Highlighting the most recent discoveries in this rapidly expanding field, the book;

• Focuses on new aspects of organopalladium chemistry, putting emphasis on synthetic applications
• Investigates the new perspectives on the synthetic uses of contemporary organopalladium chemistry

This volume, together with Innovations in Organic Synthesis, Tsuji's previous title, provides complete coverage of over 40 years of organopalladium chemistry.

Palladium Reagents and Catalysts: New Perspectives for the 21st Century is an essential reference source and companion for students, and both industrial and academic research chemists working in organic synthesis, particularly on synthesis of natural products and medicinal compounds.

Those studying development of new synthetic methodology and organometallic chemistry will also find this book valuable. ... Read more

Reviews (1)

A review of palladium chemistry
Palladium catalysts are widely used in organic synthesis and factories. This book coverd principles and applications of the palladium chemistry, and gived many examles to realize how it worked. If you worked in palladium chemistry, you must buy one! If not, you only needed to read some charpters to know the theory. ... Read more

Book Description

This is a polymer physics textbook for upper level undergraduates and first year graduate students. Any student with a working knowledge of calculus, physics and chemistry should be able to read this book. The essential tools of the polymer physical chemist or engineer are derived in this book without skipping any steps. The book is a self contained treatise that could also serve as a useful reference for scientists and engineers working woth polymers. While no prior knowledge of polymers is assumed, the book goes far beyond introductory polymer textx in the scope of what is covered. The fundamental concepts required to fully understand polymer melts, solutions and gels in terms of both static structure and dynamics are explained in detail. Problems at the end of each chapter provide the reader with the opportunity to apply what has been learned to practice. The book is divided into four parts. After an introduction in Chapter 1, where the necessary concepts from a first cours on polymers are summarized, the conformations of single polymer chains are treated in Part 1. Part 2 deals with the thermodynamics of polymer solutions and melts, including the conformations of chains in those states. Part 3 applies the concepts of Part 2 to the formation and properties of polymer networks. Finally, Part 4 explains the essential aspects of how polymers move in both melt and solution states. In all cases, attention is restricted to concepts that are firmly entrenched in the field. ... Read more

Book Description

Offers an overall introduction to the field of chemical hydrology, useful to professionals from a wide variety of training backgrounds. Provides working professionals with an all-in-one source of reference to hydrogeological literature.Brings together basic concepts from organic chemistry and microbiology to support their applications to hydrogeology and presents examples from the literature that use these concepts. The emphasis is on practical, real-world problems, with coverage ofthe theoretical basics but a focus on applications.For hydrogeologists, environmental scientists, environmental specialists, soil scientists, and hydrologists. ... Read more

Reviews (1)

Applied Chemical Hydrogeology
I purchased and used this as an alternate textbook to Drever's Geochemistry of Natural Waters for a graduate level course in Chemical Hydrogeology that I took during completion of my Masters. This is very similar and almost identical to Drever's text. This is not a text that should be used for quantitative problem solving. ... Read more

Book Description

Includes a CD allowing readers to see animated mechanisms, examine three-dimensional structures and evaluate IR spectroscopy.
* Describes numerous and frequent biomedical applications.
* Balances coverage of functional groups organization with presentation of reaction mechanisms.
* Offers clear and thorough explanations of all concepts. ... Read more

Reviews (1)

Concepts are fuzzy
I started to use this book from chapter 1-4 and I already dislike it. For instance the nomenclatature section does not explain what is the IUPAC naming for compounds pertaining functional groups well enough. The spectroscopy part, is too basic, it does not present a in-depth view of how important functional groups absorb the IR spectra. Finally, the answer that appear at the back of the book are to few, out of about 40 problems only the solution for 10 of them appear. This makes it difficult if a student wants to check an answer and does not have the solutions manual. If this book continues to be like that, I think that I might study from another book, a Professor recommended me Seyhan Ege. ... Read more

Book Description

Focuses on recent advances in research on block copolymers, covering chemistry (synthesis), physics (phase behaviors, rheology, modeling), and applications (melts and solutions). Written by a team of internationally respected scientists from industry and academia, this text compiles and reviews the expanse of research that has taken place over the last five years into one accessible resource.

• Ian Hamley is the world-leading scientist in the field of block copolymer research
• Presents the recent advances in the area, covering chemistry, physics and applications.
• Provides a broad coverage from synthesis to fundamental physics through to applications
• Examines the potential of block copolymers in nanotechnology as self-assembling soft materials

Book Description

A workbook providing additional examples, problems, and solutions for use with Warren's Organic Synthesis: The Disconnection Approach. Exercises correspond to chapters in the main text. Problems of special ease or difficulty are labeled for optional use. Workbook includes a formula index of all target molecules contained in the text and workbook. ... Read more

Reviews (5)

Retrosynthetic Analysis
Warren's Organic Synthesis-Disconnection Approach focuses on retrosynthetic analysis in organic synthesis. Some of the central concepts introduced in this strategy book are synthons, target molecule, FGI (functional group interconversion), disconnection, and reagent.

Synthons: an idealized fragment, usually a cation or an anion, resulting from a disconnection. Synthons may or may not be an intermediate in the corresponding reaction.

Disconnection: the reverse operation to a reaction. The imagined cleavage of a bond to "break" the molecule into possible starting materials.

Functional group interconversion: the process of converting one functional group into another by substitution, addition, elimination, oxidation, or reduction, and the reverse operation used in retrosynthetic analysis.

Reagent: Warren introduces a formal and rigid definition of reagent in this book. Reagent is a compound used in practice for a synthon.

Warren's treatise of organic synthesis emphasizes visualizing and choosing not only the most obvious but the most efficient disconnection (retrosynthesis) in synthesizing a target molecule. The book is set up in a fashion such that synthetic strategies and organic reactions are presented in alternating chapters. Strategies aim to enforce tricks and concepts of organic synthesis like stereoselectivity, control of regiochemistry and stereochemistry, control of carbonyl condensation, order of events in synthesis, rearrangements, use of ringed molecules. Reaction chapters present some of the most significant reactions in organic synthesis, with an emphasis of those involve carbon-carbon formation.

Topics of Warren's Organic Synthesis:
Synthesis Strategies
-The Disconnection Approach
-The Order of Events
-Chemoselectivity
-Reversal of Polarity, Cyclization Reactions
-Protecting Groups
-Choosing a Disconnection (General Strategy)
-Stereoselectivity
-Regioselectivity
-Use of Acetylenes
-Introduction of Carbonyl Condensations
-Control in Carbonyl Condensations
-Use of Aliphatic Nitro Compounds in Synthesis
-Radical Reactions in Synthesis
-Reconnections
-Introduction to Ring Synthesis, Saturated Heterocycles
-Rearrangements in Synthesis
-Use of Ketenes in Synthesis
-Pericyclic Rearrangements in Synthesis
-Special Methods for 5-Membered Rings

Reaction Methods
-One Group C-X Disconnections
-Two Group C-X Disconnections
-Amine Synthesis
-One Group C-C Disconnections: Alcohols
-One Group C-C Disconnections: Carbonyl Compounds
-Alkene Synthesis
-Two Group Disconnections: Diels-Alder Reactions
-Two Group Disconnections: 1,3-Difunctionalized Compounds and alpha,beta-unsaturated Carbonyl Compounds
-Two Group Disconnections: 1,5-Difunctionalized Compounds, Michael Addition, Robinson Annulation
-Two Group Disconnections: 1,2-Difunctionalized Compounds
-Two Group Disconnections: 1,4-Difunctionalized Compounds
-Two Group Disconnections: 1,6-Difunctionalized Compounds
-Three-Membered Rings
-Four-Membered Rings: Photochemistry in Synthesis
-Five-Membered Rings
-Six-Membered Rings
-Aromatic Heterocycles

The book teaches retrosynthetic analysis in organic synthesis. The ability to recognize an obvious and/or obscure disconnection facilitates organic synthesis tremendously. The methods and strategies presented in Warren gives advanced undergraduate students, graduate students and practicing chemists an overview of the most significant retrosynthetic pathways. Exceptional work.

The truths about this book, as I know it.
I consider myself fortunate to have had opportunities to study organic synthesis from some of the better contemporary organic chemists in the world. Here are some truths about it, regardless what was said in other comments.

1) The book presents a dissection approach in organic synthesis; that is, starting with the target compound, students learn to "go backward", "simplify", hence "dissect" the compounds into several moeities (precursors), whose precursors, in turns, can be obtained by further dissections, and so on and so forth. The process is continued until simple, common, commercially available chemicals are recognized as precursors (or starting materials). The task is then to recreate the synthetic scheme(s) to prepare the target compound, starting with these commercially available chemicals. So the comments about the book on this approach are correct.

2) In order to recognize the precursors, and recreate the synthetic schemes, students DO HAVE TO KNOW AND REMEMBER ORGANIC REACTIONS AND RELEVANT REAGENTS before they can establish a reasonable and workable dissection. So the comment that thanks to this method, students can get away with memorizing numerous organic reactions, is INCORRECT. The dissection approach simply helps us to START WITH WHAT WE WANT TO MAKE, and SYSTEMATICALLY FIGURE OUT WHAT WE NEED TO HAVE AS STARTING MATERIALS.

3) Information in the book is somewhat outdated, due to rapidly increasing number of papers published in the field of organic synthesis. However, due to limited availability of textbooks that discuss the dissection approach in organic synthesis, this book is certainly a big help for students in chemistry and chemistry-related majors.

Retrosynthesis Primer
The book treats the subject of organic retrosynthesis in a very clear fashion. It will be a perfect companion for students taking sunthetic organic chemistry course.

Great way to learn organic synthesis!
I am a grad student in a Top10 univ in US. I found Dr Warrens book an useful guide for the retrosynthtic approach to learning organic chemistry. A "must have" book..

Thinking about synthesis
Gets your mind thinking in the best way to make compounds. Instead of trying to remember hundreds of transformations, Warren's book shows you how to disconnect the compound into is smallest parts and how they could be put together. Basically, he discribes how to do retro-synthesis. Certainly another must for any medicinal or organic chemist. ... Read more

Book Description

The many exciting advances made in asymmetric synthesis over the past two decades have been due, in great part, to applications of tartaric and malic acid derivatives. Because of their unparalleled usefulness in synthesizing nonracemic acyclic and heterocyclic compounds, tartaric and malic acids are now considered indispensable "tools of the trade" for chemists working in natural products, fine chemicals, and pharmaceutical research.

Tartaric and Malic Acids in Synthesis provides chemists with a concise, yet comprehensive, review of the chemical properties and synthetic applications of derivatives of tartaric and malic acids. Intended as a source of information and inspiration, it contains a gold mine of ideas on the use of tartaric and malic acids in synthesis not only as chiral building blocks, but as chiral ligands, auxiliaries, and resolving agents as well. Throughout, the primary focus is on four-carbon building blocks derived from tartaric and malic acids and their synthetically useful reactions. Designed for ready reference, this book follows a simple, hierarchical organization-moving from derivatives of carboxy groups to derivatives of hydroxy groups, and, finally, to products of reduction of the carboxy groups-and includes:
* Hundreds of reaction schemes and figures.
* More than 70 tables with data and references for 2,000 compounds.
* Over 2,500 references to primary, secondary, and patent literature sources.

Tartaric and Malic Acids in Synthesis is a valuable working resource for chemists involved in the design of enantioselective syntheses. It is also an excellent supplementary text for graduate students of synthetic organic chemistry and natural products chemistry. ... Read more